5 citations
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January 2021 in “Journal of Saudi Chemical Society” This study analyzed watercress oil and confirmed its phytochemical profile, UV absorption properties, and potential efficacy for hair growth, supporting traditional hot oil applications.
March 2025 in “International Journal of Molecular Sciences” This study observed that topical application of palmitate or oleate accelerated the onset of the hair growth phase in mice, whereas glycolysis end product lactate delayed it, suggesting metabolic regulation as a promising approach for influencing hair growth.
195 citations
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December 2009 in “Journal of Investigative Dermatology” This study found that sebum free fatty acids may enhance the antibacterial defense of human sebaceous glands by upregulating the expression of the antimicrobial peptide hBD-2, potentially aiding in acne treatment.
38 citations
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January 2002 in “Biological & Pharmaceutical Bulletin” This study reported that the aqueous ethanol extract of Lygodii Spora demonstrated in vitro testosterone 5alpha-reductase inhibition and in vivo anti-androgenic activity, potentially due to oleic, linoleic, and palmitic acids.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.
August 2025 in “Tropical Journal of Natural Product Research” This study found that aerosols formulated with celery extract and candlenut oil significantly stimulated hair growth in rabbits without causing skin irritation, suggesting their potential as natural and safe alternatives for treating alopecia.
June 2004 in “Bulletin of Pharmaceutical Sciences. Assiut University” This study found that among natural hair loss treatments, formulations with Cantharidin in the saponifiable fraction showed superior efficacy compared to those with Pilocarpine.
6 citations
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November 2020 in “Journal of cosmetic dermatology” This study found that standardized para rubber seed oil may be a safe and effective bio-oil for stimulating hair growth and reducing hair loss, exhibiting comparable effects to minoxidil, dutasteride, and vitamin C in certain laboratory settings.
4 citations
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October 2021 in “Microorganisms” This study suggests that both the sebum composition and microbial imbalance on the scalp may play a role in the development of androgenetic alopecia among Japanese males.
3 citations
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January 2023 in “Agronomy” This research reported that KDML105 bran extract demonstrated antioxidant activities, reduced nitric oxide production, and influenced gene expression related to the hair cycle in cultured dermal papilla cells, suggesting potential as an anti-hair loss agent by supporting the anagen phase and angiogenesis.
March 2026 in “International Journal of Dermatology” In this study, researchers observed that patients with androgenetic alopecia show differences in scalp microbial communities compared to the general population, including an increase in Cutibacterium acnes, particularly in males, which may interact with lipid and immune pathways to contribute to hair follicle miniaturization.
July 2024 in “International Journal of Molecular Sciences” In this study, Nigella sativa oil was found to promote dermal papilla cell proliferation and may reduce oxidative stress, suggesting its potential as a hair loss intervention.
June 2023 in “Antioxidants” This study found that lipids extracted from Schizochytrium sp. significantly enhanced the proliferation and survival of dermal papilla cells under oxidative stress, reduced reactive oxygen species, inhibited ferroptosis, and promoted antioxidant genes, which improved hair growth in experimental settings, suggesting a potential treatment for alopecia.
January 2022 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” In this study, the application of Enriched and Enhanced Virgin Coconut Oil reportedly improved hair growth and reduced the appearance of scars in a teacher with cancer, suggesting benefits over typical post-chemotherapy recovery.
This study identified compounds like hexadecanoic acid, alphaspinasterol, and squalene in Cucurbita pepo roots, which may offer new pharmacological approaches for developing therapies for various conditions.
In this study, the fixed oil extracted from Apeiba tibourbou seeds showed potential analgesic and anti-inflammatory properties, with prominent constituents including omega-3 and omega-6 fatty acids.
7 citations
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May 2018 in “Indian Journal of Pharmacology” This study found that the methanolic extract of Carthamus caeruleus roots significantly reduced inflammation, promoted wound healing, and enhanced hair growth in experimental models, supporting its traditional use in Northern Algeria as a skincare remedy.
1 citations
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June 2023 in “International Journal of Pharmaceutical Sciences and Medicine” This review found that Sansevieria trifasciata contains numerous chemical compounds and has been traditionally used to treat various ailments, with prior studies confirming its pharmacological activities such as anti-ulcer, antibacterial, antioxidant, antidiabetic, and anticancer effects, among others.
January 2024 in “Natural product research” This study analyzed the bioactive compound profiles of Allium longisepalum from Iran, finding unique metabolites with potential antioxidant, allelopathic, antibacterial, anti-inflammatory, anticarcinogenic, and hair growth-enhancing properties, revealing the plant's chemical diversity and therapeutic potential.
April 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study identified 64 chemical compounds in the L. luteus L. plant, including several fatty acids and coumarin, highlighting the pharmacognostic potential of yellow lupine.
December 2025 in “Revista em Agronegócio e Meio Ambiente” This study investigated the effects of ultrasound-assisted extraction on sunflower seed oil mixed with defective green coffee grains, finding that higher coffee grain ratios decreased oil yield but increased phenolic content and antioxidant activity, with potential applications for wound treatment.
359 citations
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September 2017 in “European Journal of Epidemiology” This article discusses the rationale, design, and significant findings of the long-running Rotterdam Study but reports no new clinical results.
1 citations
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June 2019 in “Food Research” In this study, tempeh oil rich in PUFAs, particularly from black soybean, significantly down-regulated MMP-9 gene expression in UVB-irradiated mice skin, indicating potential for use in preventing skin photoaging.
This study used molecular dynamics simulations to illustrate the complex molecular behavior of the hair surface F-layer, highlighting how fatty acids interact with 18-MEA under different conditions.
70 citations
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February 2019 in “The journal of immunology/The Journal of immunology” This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.
47 citations
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April 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that dutasteride-loaded nanostructured lipid carriers coated with a stearic acid-chitosan oligomer are stable, less cytotoxic, and suitable for topical delivery to promote hair growth.
28 citations
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January 2018 in “Biochemical Society Transactions” This review explores the role of fatty acids and bioactive lipid mediators in skin health and suggests targeting this metabolic network to control inflammation and improve skin conditions, but it reports no new findings.
3 citations
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September 1975 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that pigs fed a fat-free diet had significantly less body dry matter and ether extract compared to those consuming a diet with corn oil, although weight gain was unaffected by the fat content.
This study suggests that 9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester from African Yam bean seeds may inhibit the human 5α-reductase II enzyme, potentially helping manage BPH, although further studies are needed.