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The conclusion is that using light-sheet fluorescence microscopy with a special solution can effectively create detailed 3D images of human skin for dermatological research.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.

The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Special fiber materials boost the healing properties of certain stem cells.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Finasteride reduces new brain cells in male mice, possibly causing depression.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Rice bran extract boosts melanin production in hair follicles.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.

FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.