Search
for

    Glossary p27Kip1

    protein that inhibits cell cycle progression by regulating CDKs

    p27Kip1, also known as p27 or CDKN1B, is a protein that helps regulate the cell cycle by inhibiting cyclin-dependent kinases (CDKs). This regulation is crucial for controlling cell growth and division, and disruptions in p27Kip1 function can lead to uncontrolled cell proliferation, which is a hallmark of cancer.

    Sort by

    Research 30 of 126

    1. Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles Journal of Dermatological Science · 2001 · 9 citations
    2. HIF‐2α/ARNT complex regulates hair development <i>via</i> induction of p21 <sup>Waf1/Cip1</sup> and p27 <sup>Kip1</sup> The FASEB Journal · 2014 · 4 citations
    3. Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes Proceedings of the National Academy of Sciences of the United States of America · 2006 · 92 citations
    4. Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair Developmental Cell · 2013 · 52 citations
    5. Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix European Journal of Cell Biology · 2017 · 30 citations
    6. Effects of dihydrotestosterone on rat dermal papilla cells in vitro European Journal of Pharmacology · 2015 · 19 citations
    7. Promotion effect of acankoreoside J, a lupane-triterpene in Acanthopanax koreanum, on hair growth Archives of Pharmacal Research · 2012 · 17 citations
    8. 참도박의 Wnt 경로 활성화를 통한 모발성장 효과 생약학회지 · 2016
    9. Hair-growth Promoting Effect of Grateloupia elliptica Via the Activation of Wnt Pathway Korean Journal of Pharmacognosy · 2016
    10. WIF1 Is Expressed by Stem Cells of the Human Interfollicular Epidermis and Acts to Suppress Keratinocyte Proliferation Journal of Investigative Dermatology · 2013 · 18 citations
    11. EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals Developmental Biology · 2012 · 53 citations
    12. Glibenclamide inhibits cell growth by inducing G0/G1 arrest in the human breast cancer cell line MDA-MB-231 BMC Pharmacology and Toxicology · 2013 · 68 citations
    13. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    14. Cyclosporin A-induced hair growth in mice is associated with inhibition of calcineurin-dependent activation of NFAT in follicular keratinocytes American Journal of Physiology-cell Physiology · 2003 · 57 citations
    15. The Promoting Effect of Ishige sinicola on Hair Growth Marine Drugs · 2013 · 26 citations
    16. Linking Morphogen and Chromatin in the Hair Follicle Developmental Cell · 2013
    17. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    18. Skin melanocytes: biology and development Postepy Dermatologii I Alergologii · 2013 · 401 citations
    19. Extraskeletal actions of vitamin D Annals of the New York Academy of Sciences · 2016 · 119 citations
    20. Molecular Regulation of Melanocyte Senescence Pigment Cell Research · 2002 · 85 citations
    21. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    22. Costunolide—A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential International Journal of Molecular Sciences · 2019 · 75 citations
    23. Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin Aging Cell · 2009 · 62 citations
    24. Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-β1 in C57BL/6 mice in vivo Growth Hormone & IGF Research · 2014 · 53 citations
    25. Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells Journal of immunology research · 2019 · 47 citations
    26. Roles of tumor suppressors in regulating tumor-associated inflammation Cell Death & Differentiation · 2014 · 44 citations
    27. Advances in the Management of Cutaneous Toxicities of Targeted Therapies Seminars in Oncology · 2012 · 42 citations
    28. Human hair keratins promote the regeneration of peripheral nerves in a rat sciatic nerve crush model Journal of Materials Science Materials in Medicine · 2019 · 36 citations
    29. The transdermal inhibition of melanogenesis by a cell-membrane-permeable peptide delivery system based on poly-arginine Biomaterials · 2014 · 36 citations
    30. Oncogenic senescence: a multi-functional perspective Oncotarget · 2017 · 32 citations