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Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Fat-related cells are important for initiating hair growth.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Wnt ligands are crucial for hair growth and repair.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

No treatment fully prevents hair loss from chemotherapy yet.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Fat tissue stem cells may help increase hair growth.

PDRN helps repair tissue and improve wound healing with a high safety profile.