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The protein p21 is more abundant in normal skin cells than in melanoma cells and may help protect against melanoma, with UVB light affecting its levels.

The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.

CDP is crucial for lung and hair follicle cell development.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.

CIP/KIP proteins help stop cell division and support hair growth.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Mice can regenerate ear tissue without the p53 protein.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Notch signalling helps skin cells differentiate and prevents tumors.

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

OR2AT4 helps reduce aging and cell damage in human skin cells.

4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.

Skin cancer often starts from Lgr5+ progenitor cells.

MicroRNAs are crucial for skin development, regeneration, and disease treatment.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.