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This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.

This study found that ectopic expression of Whn in transgenic mice caused impaired differentiation in epidermis and hair follicles, with hair growth defects and severe urinary tract issues leading to hydronephrosis.

This review discusses the senescence–stemness connection in cellular biology and reports no new findings, highlighting implications for both tissue repair and aggressive cancer behavior.

In this study, researchers found that exposure to PM10 significantly increased inflammation and impaired collagen synthesis in human dermal fibroblasts, suggesting PM10 contributes to skin aging through these mechanisms.

This review summarizes existing knowledge on androgen receptor activity in breast cancer and reports no new clinical findings, with emphasis on therapies targeting androgen signaling in specific BC subtypes.

This study found that PGD2 inhibits hair follicle regeneration in mice through the Gpr44 receptor, suggesting that blocking PGD2 or Gpr44 may enhance skin regeneration after wounds.

This study found that in vivo, a novel microneedle system for valproic acid delivery may improve hair regrowth efficacy by upregulating hair follicle development pathways more effectively than topical application.

This paper highlights the need for a comprehensive red ginseng monograph to provide standardized information on its components, certified functionality, efficacy, action mechanisms, and safety, especially given its widespread use as a health functional food in South Korea and interest in its benefits worldwide.

This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.

This review suggests that isotretinoin's effects on severe acne and various cancers may result from apoptosis, which might also explain its adverse effects through genetic variability.

Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.

This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.

This paper discusses the hypothesis that anti-acne agents may work by reducing FGFR2 signaling, and emphasizes FGFR2's potential role in acne pathogenesis, but it reports no new experimental findings.

This study found that overexpressing the BMP inhibitor Noggin in transgenic mice led to a significant loss of nontylotrich hair follicles, suggesting a critical role for BMP signaling in hair follicle morphogenesis and cycling.

This study reports that overexpressing the BMP antagonist noggin in mice inhibits eyelid opening by reducing apoptosis and delaying cell differentiation in the eyelid epithelium.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

This study found that biallelic mutations in the TTC7A gene affect lymphocyte and gut epithelial cell function, thereby contributing to the development of inflammatory bowel disease in patients.

This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.

This study suggests that finasteride may reduce the aggressiveness and invasion of prostate tumors, with effects potentially differing based on the androgen responsiveness of the patient's prostate cells.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.

This study found distinct gene expression profiles in alopecia areata-affected skin, suggesting T-cell mediated immune responses and unique gene profiles between different stages of the disease.

This study reported new crystallographic structures and polymorphs of finasteride, including several solvates with distinct X-ray diffraction patterns and thermally characterized properties.

This study demonstrates that c-MYC overexpression in sebaceous glands affects differentiation via a regulatory axis involving the androgen receptor and p53, influencing carcinoma formation outcomes.

This study found that RANK-RANKL signaling regulates hair renewal and epidermal homeostasis in mice, revealing its role in initiating hair growth cycles and maintaining skin cell activity.

This review discusses the role of peroxisome proliferator-activated receptors and their agonists in dermatology but reports no new clinical results.

This study observed that in aged mouse skin, there was an increase in IL-17-expressing T helper cells, γδ T cells, and innate lymphoid cells, and blocking IL-17 signaling reduced skin inflammation and delayed age-related changes, suggesting it as a potential target to mitigate skin aging.

This study found that AR/VDR-targeted agonist hormone therapy can inhibit cell viability in HR2-av triple-negative breast cancer cell lines through multiple mechanisms and may enhance the effects of chemotherapy.

This review discusses the multiple layers of environmental controls on hair stem cell homeostasis and suggests that targeting these layers could offer safer regenerative medicine therapies without directly using stem cells.

This review discusses the potential role of Wnt signaling in aging-related heart diseases and reports no clinical results.