research Ischemic Onycholysis of the Hands
A woman's nail separation was likely caused by poor blood flow, and a treatment for similar conditions might help.
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research Surgical Approach of Ectropion in Lamellar Ichthyosis
Surgery on a baby with a skin disorder improved eyelid position and eye health.
research Immunology and Genetics
The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.
research Tuberous Sclerosis: Clinical Findings in 57 Patients
Most patients with Tuberous sclerosis had neurological or skin issues, and over half had psychiatric problems.
research Numerous Faces of Yellow Dots: Dermatoscopic Features in Various Types of Effluvium
Yellow dots look different in various hair loss conditions and can help diagnose them.
research Dominant Dystrophic Epidermolysis Bullosa: Seven Familial Cases
The document concludes that detailed clinical descriptions of seven family cases help understand dominant dystrophic epidermolysis bullosa's symptoms and inheritance.
research Klinefelter Syndrome and Chronic Leg Ulcers
A man with Klinefelter syndrome had a leg ulcer that didn't heal well, even with treatment.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research Understanding the Functional Contribution of Dermal Stem Cells to Hair Follicle Regeneration and Skin Wound Healing
Dermal stem cells help regenerate hair follicles and heal skin wounds.
research The Role of Integrin AlphaVbeta6 in Impaired Wound Healing and Hair Follicle Regeneration
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
research New Insights into the Role of Runx1 in Epithelial Stem Cell Biology and Pathology
Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Integrated Single-Cell RNA-Sequencing Data of Unwounded and Wounded Mouse Skin and Fibroblasts
The dataset includes detailed genetic information from mouse skin cells before and after injury.
research Integrated Single-Cell RNA-Sequencing Data of Unwounded and Wounded Mouse Skin and Fibroblasts
The dataset includes detailed genetic information from mouse skin cells before and after injury.
research Peptide-Based Biomaterials
Peptides are being used to create biomaterials that can help diagnose and treat diseases.
research Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research Exosomes Mediate Sensory Hair Cell Protection in the Inner Ear
Exosomes are crucial for protecting sensory hair cells in the inner ear.
research Inhibition of Wnt/β-Catenin Pathway Promotes Regenerative Repair of Cutaneous and Cartilage Injury
Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
research Inhibition of 5-Alpha Reductase Attenuates Cardiac Oxidative Damage in Obese and Aging Male Rats via the Enhancement of Antioxidants and the p53 Protein Suppression
Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.
research Adipose Tissue in the Treatment of Androgenic Alopecia
Fat tissue can potentially treat a common form of hair loss called androgenic alopecia.
research Induction of Cellular Senescence and Hair Follicle Stem Cell Dysfunction Upon p14ARF and p16Ink4a Expression in the Skin
p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research Directed Elimination of Senescent Cells by Inhibition of BCL-W and BCL-XL
Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research The Complex Relationship Between TFEB Transcription Factor Phosphorylation and Subcellular Localization
Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
research Epidermal Notch Signaling: Differentiation, Cancer, and Adhesion
Notch signalling helps skin cells differentiate and prevents tumors.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
research Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices
Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
research Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression
Patched1 helps prevent tumors by controlling cell growth.