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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Stem cell self-renewal is complex and needs more research for full understanding.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Cathepsin L is essential for normal hair growth and development.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.