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Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.

Kids from areas with more high school dropouts have higher rates of brain injuries.

Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.

Combination therapy, especially with finasteride, is effective for treating frontal fibrosing alopecia.

DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.

Higher levels of certain DNAs in blood may indicate hair follicle damage in alopecia areata patients.

Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.

CP-690,550 significantly reduced itching in patients with moderate-to-severe plaque psoriasis.

Some teenagers with anorexia nervosa have worse cognitive abilities, especially in visual and spatial tasks, and this is more common in those with a lower body weight.

Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

5% minoxidil works better for hair growth and density, with minor irritation.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Aging causes skin stem cells to work less effectively.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.