research Skin Diseases Due to Endocrine Alterations
Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
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research Hair Pigmentation: A Research Update
Hair color is determined by different melanins and changes with age.
research Isoallopregnanolone Reduces Tic-Like Behaviors in the D1CT-7 Mouse Model of Tourette Syndrome
Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.
research Misdiagnosis as Asphyxiating Thoracic Dystrophy and CMV-Associated Hemophagocytic Lymphohistiocytosis in Shwachman-Diamond Syndrome
Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.
research Effects of the Anti-Androgen Finasteride on 5-Alpha-Reductase Activity in Human Gingival Fibroblasts in Response to Minocycline
Finasteride helps treat hair loss by blocking enzyme activity.
research Basic Mechanisms of SARS-CoV-2 Infection: Implications for Endocrine Systems
SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
research Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study
Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
research Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition
Researchers found a genetic region that influences the number of coat layers in dogs.
research Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells
Dengue virus can infect human hair follicle cells and may cause hair loss.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research Increased Risk of Fractures in Patients with Polycystic Ovary Syndrome: A Nationwide Population-Based Retrospective Cohort Study
Women with polycystic ovary syndrome have a higher risk of certain fractures.
research Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia
Finasteride side effects in young men may be linked to specific gene variations.
research Raising Threshold for Diagnosis of Polycystic Ovary Syndrome Excludes Population of Patients with Metabolic Risk
Changing the diagnosis criteria for PCOS might miss women at risk for related health issues.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Wnt Signaling Activation: Targets and Therapeutic Opportunities for Stem Cell Therapy and Regenerative Medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research Context-Dependent Effect of sPLA2-IIA Induced Proliferation on Murine Hair Follicle Stem Cells and Human Epithelial Cancer
sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
research Intestinal Permeability Study of Minoxidil: Assessment of Minoxidil as a High Permeability Reference Drug for Biopharmaceutics Classification
Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.
research Cytoskeletal Regulation of Dermal Regeneration
Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
research Nutraceutical and Functional Scenario of Wheat Straw
Wheat straw is valuable for its health benefits and various industrial uses.
research Biology of Human Hair: Know Your Hair to Control It
Understanding hair biology is key to developing better treatments for hair and scalp issues.
research Technical Procedures for Preparation and Administration of Platelet-Rich Plasma and Related Products: A Scoping Review
The review found that the way Platelet-Rich Plasma is made varies a lot, which can change the results of medical treatments.
research Platelet-Rich Plasma and Its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
Platelet-Rich Plasma (PRP) can promote new hair growth and increase hair density, but its effectiveness varies depending on the type of hair loss.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Allopregnanolone Is Required for Prepulse Inhibition Deficits Induced by D1 Dopamine Receptor Activation
Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
research The 5α-Reductase Inhibitor Finasteride Increases Suicide-Related Aggressive Behaviors and Blocks Clozapine-Induced Beneficial Effects in an Animal Model of Schizophrenia
Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.
research Molecular Basis of Androgen Action on Human Sexual Desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research The Direct Inhibitory Effect of Dutasteride or Finasteride on Androgen Receptor Activity Is Cell Line Specific
Dutasteride and finasteride affect different cell types differently.
research Alcohol Exposure During Late Adolescence Increases Drinking in Adult Wistar Rats, an Effect That Is Not Reduced by Finasteride
Alcohol in teen years leads to more adult drinking, finasteride doesn't help.
research Interventional Studies for Polycystic Ovarian Syndrome in Children and Adolescents
Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
research Metabolic Syndrome: A New Definition and Management Guidelines
New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.