January 2026 in “Revista Científica de la Facultad de Ciencias Veterinarias” This study concluded that both ozonated oil and Centella asiatica extract effectively accelerated wound healing in mice through different mechanisms, with the former enhancing early-stage inflammation and the latter promoting collagen deposition and regenerative healing.
April 2025 in “Journal of Biomedicine and Translational Research” This case report describes the successful treatment of a post-excisional biopsy dehisced wound in an 11-year-old girl using 1% framycetin sulphate tulle combined with ozonated oil as adjuvant therapy, leading to wound healing with some complications like secondary cicatricial alopecia.
January 2025 in “Letters in Drug Design & Discovery” This study found that ozonated olive oil exhibited antifungal activity against Trichophyton mentagrophytes, comparable to the standard antifungal terbinafine, in an in vivo rat study, suggesting it may serve as an alternative treatment for dermatophytosis.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that olive oil applications on the scalp may regenerate hair loss linked to SARS CoV-2 infection and vaccination, based on observations in two individuals.
July 2025 in “Journal of Research in Pharmacy” This study found that using a combination of Virgin Coconut Oil and Nigella Sativa Oil improved wound healing in diabetic rats by reducing inflammation and enhancing skin thickness compared to single treatments or controls, suggesting a potentially valuable approach for managing diabetes-related wounds.
January 2020 in “Acta Scientiae Veterinariae” In this case report, a combination of ozone therapy, low-level laser, and herbal medicine gel effectively improved healing in a dog with chronic bite wounds.
December 2025 in “Dietetics” This paper reviewed studies from 2019 to 2025 on the use of olive oil and other derivatives from the European olive tree for skin, hair, and nail care, noting their roles in wound healing and skin aging while highlighting a favorable safety profile.
December 2024 in “Journal of Population Therapeutics and Clinical Pharmacology” This review highlights the potential benefits of using rosemary and kalonji seeds for hair health, focusing on their phytochemical properties, mechanisms of action, and therapeutic potential in treating conditions such as alopecia and dandruff.
10 citations
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January 2022 in “Scholars international journal of anatomy and physiology” This review discusses Aloe Vera's traditional uses and active components but reports no new clinical results, emphasizing its potential benefits from wound healing to hair growth.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that testosterone and dihydrotestosterone can induce growth factors from dermal fibroblasts, promoting keratinocyte proliferation and differentiation, which may contribute to sex hormone-related acne development.
25 citations
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February 2017 in “Anticancer Research/Anticancer research” This review discusses the potential of ozone therapy as an adjuvant to radio-chemotherapy for cancer patients, noting enhanced treatment effects and improved quality of life, but it presents no new research findings.
December 2025 in “Cureus” This case report found that hyperbaric oxygen therapy significantly accelerated postoperative recovery in hair transplantation patients, improving healing, graft integration, and patient satisfaction without complications.
13 citations
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November 2021 in “Biomedicines” This review discusses the potential of plasma-activated liquid (PAL) in medical applications and highlights recent studies to inform researchers of its usage possibilities, but reports no new clinical findings.
December 2025 in “Veterinary Sciences” This study suggests that ozone bagging therapy may effectively enhance the healing of chronic distal limb wounds in horses, achieving full wound closure with minimal complications.
61 citations
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July 2022 in “Journal of Nanobiotechnology” This study found that carbon dots derived from fucoidan effectively inhibit Enterococcus faecalis and its biofilm, offering a promising approach for managing biofilm-associated persistent endodontic infections.
51 citations
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October 2024 in “Pharmaceutics” This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.
April 2026 in “International Journal of Molecular Sciences” This narrative review highlights the need for diabetes-informed approaches to aesthetic dermatology as accelerated skin aging in diabetic patients complicates the safety and effectiveness of cosmetic procedures.
March 2026 in “Preprints.org” This study reviews how individuals with diabetes experience accelerated skin aging and explores the implications for cosmetic treatments, highlighting the need for diabetes-informed dermatologic approaches due to limited evidence on safety and efficacy in this population.
May 2026 in “International Journal of Cosmetic Science” This study found that repeated exposure to ozonated water caused oxidative changes in hair proteins, lipids, and pigments, leading to altered hair properties, with minimal effects on shine and color.
1 citations
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May 2024 in “International journal of medicine and psychology.” In this study, researchers found that using electromagnetic radiation in the EHF range enhanced the engraftment of skin flaps in rats by improving microcirculation and reducing necrosis, with greater effects observed when paired with systemic ozone therapy.
13 citations
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May 2009 in “Ozone Science and Engineering” This study found that while ozonized olive oil inhibited swelling in a mouse model of hypersensitivity, it also induced inflammatory responses and hair loss with repeated skin application, indicating potential adverse effects.
In this study, ozonized sunflower oil effectively healed skin wounds in a dog and a cat over 30 and 50 days, respectively, with no side effects, showing faster hair regrowth and improved local metabolism.
93 citations
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February 2008 in “Atmospheric environment” In this study, researchers found that human scalp hair, particularly when unwashed, can significantly react with ozone, reducing personal ozone exposure and increasing exposure to volatile reaction products.
September 1995 in “PubMed” This study found that ozonized autohaemotherapy improved the hair cycle in individuals with androgenetic alopecia.
6 citations
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August 2024 in “The Journal of Dermatology” In this study, ozenoxacin was found to inhibit sebum production in insulin- and 5α-DHT-differentiated hamster sebocytes in a dose-dependent manner, suggesting potential benefits in acne management by combining antimicrobial activity against C. acnes with reduced sebum production.
November 2025 in “Undersea and Hyperbaric Medicine” This case report observed that a patient experienced worsening alopecia and scarring after medical ozone therapy, with subsequent improvement following surgical intervention and systemic hyperbaric oxygenation.
December 2025 in “PubMed” This case study reported that a patient experienced worsening alopecia and scarring after medical ozone therapy, highlighting significant clinical risks that may outweigh potential therapeutic benefits.
February 2022 in “Journal of Cosmetic Dermatology” This study found that pre-treating hair with argan oil reduced protein loss and provided protection against oxidative damage, supported by both ATR spectrum analysis and protein measurements.
December 2024 in “International Journal of experimental research and review” This study developed a stable nanoemulsion using ultrasonic vibrations and Tween 80 emulsifier, which can enhance the antibacterial activity and prolong the shelf life of food products, as well as be applicable in cosmetics and pharmaceuticals for oral and transdermal use.
August 2018 in “Journal of The American Academy of Dermatology” Ozenoxacin 1% cream is an effective and safe treatment for impetigo in children and adults.