5 citations
,
June 2024 in “Free Radical Biology and Medicine” This review highlights that current in vitro models often fail to replicate the physiological oxygen levels experienced by different skin cell types, which could affect redox states and functions, potentially accelerating skin aging.
35 citations
,
August 2016 in “Experimental Dermatology” This viewpoint essay discusses the potential of fullerene C60 derivatives as novel treatment agents in dermatology, highlighting their ability to act as both radical scavengers and oxygen radical generators.
52 citations
,
May 2011 in “APOPTOSIS” In this study, cisplatin was found to induce cell death in human hair follicle cells through hydroxyl radical generation and Bcl-2 down-regulation, suggesting potential strategies for preventing chemotherapy-induced alopecia.
January 2023 in “Journal of Ravishankar University” This review discusses the role of oxidative stress and reactive oxygen species in the development of androgenic alopecia and reports no new clinical findings.
31 citations
,
January 2011 in “Dermato-endocrinology” This review updates the protective effects and molecular mechanisms of melatonin against ultraviolet-induced damage in human skin, reporting no new clinical findings.
February 2008 in “Experimental dermatology” This article reviews potential pathomechanisms of vitiligo, emphasizing membrane alterations involving cholesterol and cardiolipin, but reports no new clinical findings.
4 citations
,
January 2018 in “Cosmetics” This review discusses the potential use of spin traps in cosmetic products to limit reactive oxygen species generated by pollution, emphasizing the need for further research due to toxicity and regulatory concerns.
4 citations
,
November 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study found that a hydro-alcoholic extract of Roselle petals may reduce free radical production during UV-induced photodecomposition of antibiotics, potentially offering protective benefits for patients using similar topical antibiotics.
24 citations
,
July 2015 in “Molecular Medicine Reports” This study found that lysophosphatidic acid increases mesenchymal stem cell proliferation and migration through signaling pathways and reactive oxygen species, implicating potential applications in stem cell expansion.
10 citations
,
January 2004 in “Dermatologic Surgery” This study found that storing hair follicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.
January 2004 in “Dermatologic Surgery” This study found that storing hair micrografts in DMEM with apoptotic cell death inhibitors improved in vitro hair shaft elongation and reduced apoptosis, potentially enhancing micrograft transplantation outcomes.
2 citations
,
February 2004 in “Biopolymers” This study found that 4-(4-Phenoxybenzoyl)benzoic acid derivatives may act as antioxidants by scavenging certain reactive oxygen species but exhibit prooxidant behavior under specific conditions.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that Ginseng and Albizia extracts, when used together, protected human dermal papilla cells from oxidative stress-induced senescence, and inhibited genes that suppress hair growth, indicating their potential in preventing age-related hair density reduction.
7 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study found that patients with androgenetic alopecia had increased oxidative stress and microinflammation, contributing to hair loss, due to elevated levels of specific serum biomarkers compared to controls.
44 citations
,
October 2019 in “International Journal of Molecular Sciences” This article reviews various studies and suggests that melatonin, produced both naturally in the skin and applied topically, may offer significant protection against environmental damage, making it a promising candidate for skincare therapies.
57 citations
,
March 2024 in “Nano-Micro Letters” In this study, researchers created a core-shell nanozyme, CeO2@ZIF-8/Au, which autonomously regulates ROS levels to efficiently eliminate bacteria, reduce inflammation, and promote wound healing by balancing ROS generation and scavenging in response to environmental conditions.
56 citations
,
September 2013 in “Journal of Biochemistry and Molecular Biology” This study observed that androgen treatment increased ROS production and TGF-β1 secretion in rat hair follicle dermal papilla cells, suggesting that the androgen-induced TGF-β1 is mediated by ROS.
49 citations
,
January 1998 in “International Journal of Molecular Medicine” In this study, lipid peroxides were found to induce apoptosis in hair follicle cells and advance the catagen phase in mice, suggesting a potential mechanism for alopecia development.
295 citations
,
March 2016 in “Life Sciences” This review discusses the links between particulate matter exposure and skin diseases, highlighting oxidative stress and inflammation as key mechanisms; it reports no new clinical results.
17 citations
,
July 2013 in “Amino Acids” This study found that elevated epidermal ODC activity in transgenic mice promotes skin tumor development by recruiting bulge stem cells, rather than through reactive oxygen species generation by polyamine catabolic oxidases.
2 citations
,
November 2018 in “International Journal of Cosmetic Science” This study proposes a simple fluorescence method to evaluate hair damage and protection, suggesting that emissive properties of hair can aid in substantiating cosmetic claims.
63 citations
,
February 2013 in “Human cell” In this study using an animal model, researchers found that PEGL-DOX, unlike DOX, causes Hand-Foot Syndrome due to reactive oxygen species interacting with skin tissue, leading to skin-specific inflammatory responses.
2 citations
,
September 2022 in “Cellular and molecular biology” In this study, Agaricus bisporus derived β-Glucan particles demonstrated antimicrobial, antioxidant, and anticancer effects against cervical cancer HeLa cells, suggesting potential as a therapeutic option.
37 citations
,
November 2020 in “International Journal of Nanomedicine” Nano-liposol with astaxanthin may improve antioxidant and wound healing effects.
9 citations
,
November 2024 in “Journal of Wound Management Official journal of the European Wound Management Association” Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
62 citations
,
July 2022 in “Science Immunology” This study discovered that TREM2 macrophages influenced by squalene play a role in acne's development by hindering the killing of Cutibacterium acnes, helping explain why benzoyl peroxide is effective in treatment.
20 citations
,
February 2022 in “Pharmaceutics” This study found that idebenone-loaded nanoparticles (IB@NPs) improved stability, antioxidant activity, and wound healing capacity in vitro, suggesting potential applications in cosmetic and pharmaceutical fields.
4 citations
,
December 2023 in “Advanced science” This study found that injectable gelatin/metal/tea polyphenol double nanonetworks significantly accelerated wound healing in diabetic wounds by enhancing cell migration and providing anti-inflammatory and antioxidant properties, without detectable cytotoxicity in tests.
2 citations
,
February 2022 in “Biology” This study found that blue laser irradiation reduced ATP levels and cell viability in mouse skin by increasing oxidative stress through the production of reactive oxygen species.
March 2026 in “Science China Materials” SeV-Tp speeds up healing of drug-resistant infections by targeting wounds and killing bacteria with light activation.