research Scalp Application of the Antioxidant Piroctone Olamine Reduces Hair Shedding in an 8-Week Randomized, Double-Blind, Placebo-Controlled Clinical Study
Using piroctone olamine on the scalp helps reduce hair loss and improves scalp health.
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research Evaluation of a Combination of Botanical Extracts Designed to Protect Hair and Scalp from Air Pollutants: In Vitro and Clinical Studies
Botanical extracts from peas and chia seeds improved scalp health and protected hair from pollution.
research A Novel Multi-Targeting Approach to Treating Hair Loss Using Standardized Nutraceuticals
A new supplement may treat hair loss by targeting multiple causes like inflammation and stress.
research Effect of Alpha Lipoic Acid on Smoking-Induced Skin Damage
Alpha Lipoic Acid helps protect skin from smoking damage.
research Exploring the Interplay Between Arsenic and Cutaneous Physiology, Pathology, and Regeneration
Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
research Unexpected Expression of Hemoglobin Alpha as an Endogenous Antioxidant in Epidermal Keratinocytes
Hemoglobin α acts as an antioxidant in skin cells, especially protecting hair follicle stem cells from UV damage.
research Hair Growth-Promotion Effects at the Cellular Level and Antioxidant Activity of the Plant-Based Extract Phyllotex
Phyllotex™ extract was found to significantly promote hair growth and protect against hair loss.
research Environmental Pollution, Oxidative Stress, and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride, and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis, and Aging
Environmental pollutants like glyphosate, fluoride, and electromagnetic fields can cause health problems by damaging mitochondria and affecting metabolism.
research Protective Efficacy of Vitamin F Against Acrylamide-Induced Toxicity: Studies on Oxidative Stress Biomarkers
Linoleic acid (Vitamin F) can help protect against the harmful effects of acrylamide.
research Administration of Nrf-2-Modified Hair-Follicle MSCs Ameliorates DSS-Induced Ulcerative Colitis in Rats
Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
research Polyphenol-Rich Olive Mill Wastewater Extract and Its Potential Use in Hair Care Products
Olive Mill Wastewater extract could potentially improve hair growth and prevent hair loss.
research Transient Stimulation of TRPMLs Enhances the Functionality of HDPCs and Facilitates Hair Growth in Mice
Activating TRPMLs helps human cells important for hair growth and increases hair growth in mice.
research Change in Surface Chemistry of the Cuticle of Human Hair by Chemical and Photochemical Oxidation
Oxidation changes human hair by breaking down fats and forming new acidic groups, affecting how it interacts with conditioners and cosmetics.
research Hair Follicle Rejuvenation Induced by Topical Minoxidil in a Humanized Mouse Model of Androgenetic Alopecia
This study investigated the effects of minoxidil on hair follicle aging in male pattern androgenetic alopecia (mpAGA) using human scalp transplants from 9 patients on SCID/beige mice. The results showed that 5% topical minoxidil treatment for four months significantly upregulated anti-aging markers such as PGC1α, SIRT1, MTCO-1, and VDAC in the hair follicles. It also increased collagen 17A and lamin B1, reduced the expression of the senescence marker p16INK4a, and decreased mTOR activity. Additionally, minoxidil enhanced antioxidant enzyme activity and VEGF-A protein expression, suggesting its potential as an anti-aging agent that mitigates oxidative damage and promotes hair follicle rejuvenation in mpAGA.
research Coffee Silverskin: A Review on Potential Cosmetic Applications
Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Melatonin in the Skin: Synthesis, Metabolism, and Functions
Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
research Modulation of Genomic and Postgenomic Alterations in Non-Cancer Diseases and Critical Periods of Life
N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.
research The Potential of Resveratrol-Rich Peanut Callus Extract in Promoting Hair Growth and Preventing Hair Loss
Peanut callus extract helps grow hair and prevent hair loss.
research Notes From The Editor Emeritus, 2011–2013
Caffeine can stimulate hair growth, but the best dose and frequency for hair loss treatment are still unknown.
research MG53 Mitigates Nitrogen Mustard-Induced Skin Injury
MG53 helps reduce skin damage caused by nitrogen mustard.
research Possible Role of Autophagy Activation in Stimulation of Regeneration
The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.
research Advanced Glycation End-Products Inhibit Mesenchymal-Epidermal Interaction by Up-Regulating Proinflammatory Cytokines in Hair Follicles
AGEs may cause hair loss by increasing inflammation in hair follicles.
research Indian Gooseberry (Emblica Officinalis Gaertn.) Pharmacological Properties
Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
research Injectable Photocuring Silk Fibroin-Based Hydrogel Constructs Antioxidant Microenvironment for Skin Repair
The hydrogel helps skin heal faster and better than a commercial dressing by creating a protective environment and supporting new blood vessel and hair growth.
research Dermatoprotective Effect of Moringa Oleifera Leaf Extract on Sodium Valproate-Induced Skin Damage in Rats
Moringa oleifera leaf extract protects skin from damage caused by sodium valproate.
research Injectable Gelatin/Metal/Tea Polyphenol Double Nanonetworks for Diabetic Wound Healing
New injectable hydrogels with gelatin, metal, and tea polyphenols help heal diabetic wounds faster by controlling infection, improving blood vessel growth, and managing oxidative stress.
research Novel Association of Trichothiodystrophy With Autoimmune Thyroiditis and Autoimmune Hemolytic Anemia: A Case Report
A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.
research A Six-Month, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of a Nutraceutical Supplement for Promoting Hair Growth in Women With Self-Perceived Thinning Hair
Nutrafol® Women's Capsules safely and effectively promote hair growth in women with thinning hair.
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.