February 2026 in “International Journal of Molecular Sciences” This study found that PDLLA filler treatment may help combat age-related hair thinning by reducing oxidative stress and enhancing hair follicle function in both cell and animal models.
January 2026 in “Molecules” In this study, the novel thiol-Michael click perming molecule, MA2-CySS, achieved repeatable perming with reduced oxidative damage, preserving hair keratin's structure while maintaining efficiency comparable to traditional oxidative methods.
January 2026 in “Brazilian Journal of Pharmaceutical Sciences” This study assessed the effects of chemical treatments on hair fiber integrity and found that conditioners with vegetable oils like jojoba and coconut enhanced hydrophobicity and reduced combing friction except for jojoba, while participants preferred these oil-containing conditioners over the base formulation.
August 2025 in “Applied Sciences” This study found that peroxide-rich plasma-activated water caused minimal morphological damage to hair, while nitrate-rich plasma-activated water induced significant damage, especially in porous hair types.
July 2025 in “Journal of Drug Delivery and Therapeutics” This review discusses how pesticide exposure leads to hair loss and explores therapeutic options, including conventional and gene therapies, as well as herbal remedies like ginseng and green tea, which may counteract these effects by addressing the toxicological impact on hair follicles.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.
January 2025 in “Antioxidants” In this study, repetitive subcutaneous administrations of a conditioned medium from stem cells significantly suppressed hair graying in mice exposed to X-ray irradiation, likely through antioxidative mechanisms involving HGF and potentially VEGF.
August 2024 in “Applied Sciences” This review explored the causes of hair graying and evaluated how plant-derived extracts and phytochemicals might alleviate it, noting that certain compounds showed potential in enhancing melanocyte function, reducing oxidative stress, and influencing stress-related pathways based on experimental evidence.
June 2024 in “Molecules/Molecules online/Molecules annual” This study found that Platycladus orientalis flavonoids may reduce oxidative damage and slow melanin degradation in AGA-affected hair, improving its quality.
June 2024 in “Journal of Clinical Medicine” This case study and literature review highlights a chemical burn from hair dye experienced by a 17-year-old girl, resulting in a long-term scalp ulcer. It emphasizes the need for careful consideration of scalp complications and a multidisciplinary treatment approach in hair dye procedures.
67 citations
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September 2017 in “Cell Reports” Caloric restriction improves skin and fur structure but can cause muscle loss and movement issues.
22 citations
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November 2023 in “Clinical Cosmetic and Investigational Dermatology” This review examines the potential mechanisms by which stem cell-derived cell-free therapy may prevent skin aging, highlighting various molecular targets and pathways involved in regeneration, oxidative stress regulation, ECM preservation, cell activity modulation, and inflammation.
6 citations
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April 2022 in “Biomedicine & pharmacotherapy” This review discusses the potential of using triads of repositioned medicines targeting multiple pathogenic mechanisms to prevent or delay retina degeneration, but reports no new results.
This review highlights that iron deficiency is a significant yet often overlooked contributor to the development of immune-mediated inflammatory skin diseases, suggesting that iron dysregulation may drive inflammation and metabolic imbalances in conditions like psoriasis and atopic dermatitis.
October 2025 in “Cell Proliferation” In laboratory research, investigators found that apoptotic vesicles from interleukin-10-treated fibroblasts promote wound healing and reduce fibrotic scarring by enhancing mitochondrial function, modulating collagen composition, and inhibiting the Hedgehog signalling pathway, offering potential for regenerative medicine applications.
1 citations
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June 2016 in “Experimental Dermatology” This article discusses advancements in proteomic and metabolomic analysis techniques for studying hair damage but provides no new clinical results; the authors express interest in applying metabolomics to develop strategies for reducing hair damage from chemical treatments.
2 citations
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July 2023 in “Cosmetics” In this study, researchers highlighted that while hair lipids are crucial for hair health and protection, surfactants in shampoos and conditioners can partially remove these lipids, potentially affecting hair structure, though the exact mechanisms remain poorly understood and require further investigation.
9 citations
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July 2022 in “Journal of Cosmetic Dermatology” In this study, an ammonia-free and PPD-free permanent hair dye was tested on 50 ethnically diverse females, showing no cases of contact dermatitis and significant improvements in hair shine, color, moisturization, porosity, and combability after two dyeing sessions.
January 2026 in “SSRN Electronic Journal” Riboflavin with blue light speeds up hair dyeing, making it faster, safer, and long-lasting with less hair damage.
October 2023 in “Nutrients” This study suggests that a complex of millet and wheat extract may enhance hair health by reducing oxidative stress and inflammation and potentially prolonging the anagen phase of hair growth in models.
43 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews innovations in hair cosmetics, focusing on esthetic procedures and products in the Indian market, and reports no new experimental findings.
12 citations
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January 2020 in “Analyst” This study found that untargeted hair metabolomics analysis detected significantly altered endogenous biomolecules, potentially serving as biomarkers for identifying oxidative cosmetic hair treatments like bleaching.
2 citations
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May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that stem cells can temporarily act as non-professional phagocytes during hair cycle regeneration by clearing apoptotic cells through a process requiring local lipids and retinoids for activation, providing insights into their dual role in maintaining tissue integrity.
8 citations
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January 2009 in “Transactions of the Materials Research Society of Japan” This study found that CMAD wool keratin may protect human hair from damage during repeated bleaching and permanent waving treatments.
1 citations
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July 2016 in “Cosmetics” This review highlights a case of cross sensitization to dyes from temporary henna tattoos and stresses the need for public awareness on the risks associated with these tattoos.
8 citations
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March 2015 in “Molecular Medicine Reports” This study found that para-phenylenediamine induces cytotoxic effects in normal human hair dermal papilla cells by altering microRNA expression and causing cell death, cell cycle arrest, and oxidative stress.
September 2025 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” In this review, researchers explored the complex mechanisms behind chemotherapy-induced side effects like nausea, fatigue, and hair loss, and discussed potential strategies using natural agents to manage these toxicities, improving understanding for targeted adjunct therapies.
April 2024 in “Cell death and differentiation” This study discusses how different modes of regulated cell death in keratinocytes affect skin stem cell niches, and their role in skin inflammation, injury repair, and cancer, based on findings from human dermatological conditions and experimental mouse models.
40 citations
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February 2002 in “International Journal of Dermatology” In this study, hair damaged by permanent dye showed signs of recovery over time, with near complete restoration to its original state after eight weeks.
June 2026 in “Studia Biologica” This study found that in semi-coarse wool sheep of the Ukrainian Carpathian Mountain breed, changes in microflora and grease composition are linked to increased felting in wool, due to wetter, more alkaline fleece conditions that promote bacterial and mold growth and alter fatty acid balances.