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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Melatonin protects skin against UV damage by regulating various cellular processes.

Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.

Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.

Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.

Human hair protein modifications could potentially indicate heart disease risk.

Roselle flower extracts can protect against free radical damage in UV-irradiated antibiotics.

Controlled light treatment in mouse skin speeds up healing and hair growth.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Myrtle has various health benefits and potential for medicine development.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.