February 2022 in “Journal of Cosmetic Dermatology” This study found that pre-treating hair with argan oil reduced protein loss and provided protection against oxidative damage, supported by both ATR spectrum analysis and protein measurements.
3 citations
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January 2015 in “Turkiye Klinikleri Journal of Medical Sciences” The researchers reported that corticosteroid treatments for alopecia areata led to clinical improvement but did not significantly alter oxidative stress markers, suggesting a limited regulatory effect on these systems.
May 2026 in “Brazilian Journal of Hair Health” This study found that bleaching significantly damages hair structure and increases combing difficulty, while dyeing with emulsifiers can partially reduce damage and improve combability, yet both processes cause notable protein loss.
70 citations
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June 1998 in “Polymer” This study found that permanent waving treatment partially disrupts the α-helical structure in human hair microfibrils, primarily during the initial reduction phase, rather than just affecting disulphide bonds.
2 citations
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January 2023 in “Frontiers in Oncology” In this rat study, subcutaneous injections of hydrogen peroxide and cumene hydroperoxide appeared to completely prevent chemotherapy-induced hair loss by inducing cell cycle arrest, suggesting a novel approach to help cancer patients maintain their quality of life during treatment.
February 2023 in “Frontiers in Bioengineering and Biotechnology” This review discusses the potential of optical techniques for diagnosing and treating oxidative stress-related hepatic ischemia-reperfusion injury, highlighting the need for non-invasive diagnostic methods and the anti-oxidative potential of optical therapies; it reports no new clinical results.
4 citations
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January 2007 in “Sen'i Gakkaishi” This study found that permanent wave treatment accelerates hair degradation after protease exposure, showing significant morphological differences compared to untreated hair and linked to damage from Alpha-helical region denaturation.
9 citations
,
October 1993 in “The Journal of Clinical Pharmacology” Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
3 citations
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September 2024 in “Brain and Behavior” This study found that combining ASA with conditioned medium from adipose tissue-derived MSCs may offer a promising approach for protecting against hippocampal injuries, suggesting potential synergistic therapeutic benefits that merit further investigation.
October 2021 in “Technology transfer: innovative solutions in medicine” This study found that combining platelet-rich plasma injections with topical 2% minoxidil for three months normalized certain immunohistochemical parameters in female patients with early-stage androgenetic alopecia.
25 citations
,
December 2011 in “Surface and interface analysis” This study reports that hair damage from bleaching is associated with the oxidative cleavage of fatty acid thioester bonds, detectable by measuring the decrease in mass spectrometry peak at m / z 76.
September 2021 in “Eureka: Health Sciences” This study found that female androgenetic alopecia is linked to oxidative stress, microinflammation, and fibrosis, suggesting these could be key targets for treatment improvements.
99 citations
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June 2005 in “Journal of Cosmetic Dermatology” This article reviews factors influencing hair aging and available treatments like minoxidil and finasteride for androgenetic alopecia but reports no new clinical results.
36 citations
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October 2014 in “Langmuir” This study concluded that bleach treatment partly transforms the hydrophobic top layer of human hair cuticles into a hydrophilic surface with clustered cysteic acid, visualized at the nano-scale using dynamic Chemical Force Microscopy.
8 citations
,
March 2020 in “Metabolites” This study found differences in urinary androgen and estrogen concentrations between male pattern baldness patients treated with finasteride and healthy controls, suggesting potential biomarkers for post-finasteride syndrome.
March 2023 in “Chinese Journal of Dermatology” Protecting hair and scalp from sunlight may help prevent hair loss.
24 citations
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January 2009 in “International Journal of Trichology” This review discusses the mechanisms by which sunlight exposure aggravates hair aging and highlights the role of hair pigments in providing photochemical protection, reporting no new results.
February 2026 in “American Scientific Research Journal for Engineering, Technology, and Sciences (Global Society of Scientific Research and Researchers)” This study analyzed gray hair, revealing that it differs from pigmented hair in follicular activity, oxidative balance, and structure, impacting coloring processes and necessitating adapted techniques to maintain hair quality.
30 citations
,
September 2018 in “International Journal of Cosmetic Science” In this study, researchers observed that cosmetic peroxide bleaching causes oxidative damage and protein loss in human hair, not only affecting the cuticle but also deeper cortical structures, correlating with bleaching severity.
21 citations
,
October 2014 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses the role of hair dyes in cosmetic dermatology, their effects on hair and scalp health, and the importance of dermatologists understanding potential side effects; it reports no new findings.
3 citations
,
January 2020 in “Plastic and Aesthetic Research” This review discusses the fundamental hallmarks of aging as they relate to skin aging and highlights the prominent roles of oxidative damage and the extracellular matrix in photoaging, reporting no new results.
1 citations
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April 2024 in “Food Frontiers” In this study involving mice, the researchers observed that circadian rhythm disorder can pass alopecia risk to male offspring, and parental Pu-erh tea consumption, particularly by females or both parents, mitigated this risk through various biological mechanisms.
February 2026 in “Brazilian Journal of Implantology and Health Sciences” This integrative literature review revealed that chronic stress, characterized by elevated cortisol levels, negatively impacts hair follicle integrity and contributes to alopecia by promoting the premature transition from the growth phase to the resting phase of the hair cycle.
March 2025 in “International Journal of Pharmaceutical Research and Applications” This study highlights recent biological and technological strategies in anti-aging research aimed at delaying aging and related diseases, improving skin healing, and potentially restoring hair growth.
November 2023 in “Frontiers in cell and developmental biology” This source reviews mechanisms and existing treatments for hair aging, highlighting factors like oxidative stress and DNA repair defects that affect hair follicle and stem cell function, and discusses research limitations and future directions in the field.
This study found that tenuazonic acid from Alternaria alternata can cause significant damage to vital organs in mice at low doses and highlights the need for regulatory measures to manage its risk in agricultural products.
March 2013 in “Molecular & Cellular Toxicology/Molecular & cellular toxicology” In this study, exposure to m-Aminophenol in human keratinocytes altered the expression of thousands of genes involved in inflammation and stress responses, suggesting potential biomarkers for MAP-induced skin toxicity.
39 citations
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June 2012 in “Journal of Structural Biology” Disulfide bonds are crucial for hair structure during keratinization.
September 2010 in “International Journal of Cosmetic Science” This study describes a microfluorometric method to quantify lipid removal and reattachment on human hair during light exposure and chemical treatments, altering hair surface properties from hydrophobic to hydrophilic.
February 2025 in “European Journal of Dermatology” This review explored the complex mechanisms behind androgenetic alopecia, highlighting genetic influences and factors like increased 5-α reductase and androgen receptors in hair follicles, while identifying microinflammation and oxidative stress as related issues.