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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

The document explains how male reproductive hormones work and affect the body.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

PCOS treatment should address both symptoms and metabolic risks, starting with lifestyle changes and possibly including medication.

The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.

The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.

PCOS increases the risk of heart disease and type 2 diabetes in women.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Hirsutism is often caused by high male hormone levels and can be treated with lifestyle changes and medications.

The Hairless gene is crucial for healthy skin and hair growth.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

Certain changes in the VEGF gene can increase or decrease the risk of polycystic ovary syndrome.

The new rodent model successfully mimics non-lean human PCOS symptoms.

Proper nutrition can help manage PCOS symptoms and improve overall health.

Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

SkQ1 antioxidant improved health and lifespan in mice.