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New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.

Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.

The study found three different timing patterns of symptoms in women with premenstrual dysphoric disorder.

Metformin helped improve the quality of life for Chinese women with PCOS, especially in physical health and symptoms like infertility, acne, and hair loss.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.

Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Women with PCOS have higher levels of a certain growth factor, which can be reduced by taking metformin.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.

Oral contraceptives may cause hair loss in women.

Timing of light therapy affects horse coat growth, with photoperiod being crucial.

Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.

High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.

AMH is a good marker for diagnosing PCOS, but global standards are needed.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.