research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency
Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.
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research Volatile Organic Compounds: A Proinflammatory Activator in Autoimmune Diseases
Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.
research MTORC1 Activity Negatively Regulates Human Hair Follicle Growth and Pigmentation
High mTORC1 activity slows hair growth and causes it to lose color.
research Hidradenitis Suppurativa: A Folliculotropic Disease of Innate Immune Barrier Dysfunction?
Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
research Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration During Wound Healing
Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson-Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies
Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
research Immunohistochemical, Pharmacovigilance, and Omics Analyses Reveal the Involvement of ATP-Sensitive K+ Channel Subunits in Cancers: Role in Drug-Disease Interactions
ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
research Bipolar Patients and Bullous Pemphigoid After Risperidone Long-Acting Injectable: A Case Report and Literature Review
Long-term use of Risperidone may be linked to a serious skin condition in bipolar patients, affecting their overall well-being.
research Glycosaminoglycans’ Ability to Promote Wound Healing: From Native Living Macromolecules to Artificial Biomaterials
Glycosaminoglycans help heal wounds but aren't yet ready for clinical use.
research The Roles of WNT Signaling Pathways in Skin Development and Mechanical-Stretch-Induced Skin Regeneration
WNT signaling is crucial for skin development and healing.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Dermal Hedgehog Signaling in Papillary Fibroblasts: An Emerging Key Player in Skin Regeneration
Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Keeping β-catenin levels high in mammary cells disrupts their development and branching.
research Exosomes: A Promising Strategy for Repair, Regeneration and Treatment of Skin Disorders
Exosomes could be a promising way to help repair skin and treat skin disorders.
research Human Regulatory T Cells: Role in Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research The Multiple Consequences Of Obesity
Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
research Keratinocyte Stem Cells: Role in Aging
Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
research The Immune System Response in COVID-19 Infection in Polycystic Ovary Syndrome
Women with PCOS may have a higher risk of severe COVID-19 due to hormonal imbalances and vitamin D deficiency.
research Spreading of Isolated Ptch Mutant Basal Cell Carcinoma Precursors Is Physiologically Suppressed and Counteracts Tumor Formation in Mice
External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.
research Chemistry, Pharmacology, and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Oxidative Stress: Insights into the Pathogenesis and Treatment of Alopecia
Hair loss can be caused by stress, aging, and harmful substances that create an imbalance in the body's natural processes.
research Life Sciences Discovery and Technology Highlights
New findings suggest certain genes and microRNAs are crucial for wound healing, and innovative technologies like smart bandages and apps show promise in improving treatment.
research Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology
The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
research Update From 2017 Embracing The World Of Dermatology Convention
The convention highlighted knowledge sharing, networking, and the importance of active participation in dermatology.
research Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells
Stress causes hair graying by overactivating nerves that deplete color-giving stem cells.
research Lignans and Neolignans: Plant Secondary Metabolites as a Reservoir of Biologically Active Substances
Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
research Identifying Novel Strategies for Treating Human Hair Loss Disorders: Cyclosporine A Suppresses the Wnt Inhibitor, SFRP1, in the Dermal Papilla of Human Scalp Hair Follicles
Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
research Interventions for Central Serous Chorioretinopathy: A Network Meta-Analysis
The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.