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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Ayurveda's descriptions of genetic disorders align with modern genetic understanding.

Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.

Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

Skin symptoms can indicate endocrine disorders and have various treatments.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Most women with excessive hair growth have a hormonal cause.

The case showed the need for quick investigation of virilization in women and how emotional health is linked to physical health.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

PRP therapy helps skin heal and improve by promoting cell growth and repair.

Diagnosing PCOS is challenging due to its complex and varied symptoms.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Removing one ovary helped treat a woman's severe PCOS symptoms when medicine didn't work.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

New therapies are being developed that target integrin pathways to treat various diseases.

Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.