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Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Meis1 is crucial for skin health and tumor development.

Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

The PCOS-specific questionnaire needs more work to fully measure quality of life in clinical trials.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Chemotherapy causes hair loss starting soon after treatment begins and recovers about 3 months after ending, while tamoxifen does not significantly affect hair growth.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.

Birth control pills can help manage acne, but dermatologists should know their skin-related side effects, especially when prescribing drugs that can harm unborn babies.

Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Small molecule IM boosts hair growth by changing stem cell metabolism.