60 citations
,
May 2011 in “Endocrinology and Metabolism Clinics of North America” This article discusses the association between hypertension and polycystic ovary syndrome, highlighting the need for managing related risk factors, but reports no new clinical results.
53 citations
,
February 2022 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This review discusses the use of antimüllerian hormone as a marker of ovarian reserve in infertility diagnosis and treatment, noting it reflects oocyte quantity but not health or pregnancy likelihood.
49 citations
,
November 2019 in “Egyptian Journal of Medical Human Genetics” This review discusses the role of CYP gene polymorphisms in exacerbating hyperandrogenism in women with PCOS and reports no clinical results; further validation of this hypothesis is needed.
38 citations
,
May 2006 in “Archives of Gynecology and Obstetrics” This study reported that women with PCOS had higher levels of certain hormones and lower SHBG levels compared to non-PCOS women with similar symptoms, highlighting a less favorable endocrine profile in PCOS cases.
34 citations
,
January 2008 in “International Review of Neurobiology” This review discusses the interplay between epilepsy and reproductive endocrine disorders, examining the factors involved and emphasizing the importance of monitoring but reports no new research findings.
28 citations
,
October 2013 in “Journal of The American Academy of Dermatology” In this study, ovarian SAHA was found to be independently associated with a more insulin-resistant profile and increased risk of glucose abnormalities in women with PCOS, beyond common risk factors.
24 citations
,
September 2001 in “Journal of The American Academy of Dermatology” Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
21 citations
,
July 2019 in “Cardiovascular Research” This study found that prenatal exposure to androgens caused long-lasting heart remodeling and left ventricular hypertrophy in female mice offspring, suggesting potential cardiac risks for daughters of mothers with PCOS.
20 citations
,
September 2020 in “International journal of computer applications” This study found that the Random Forest machine learning algorithm achieved the highest accuracy, 96%, in diagnosing Polycystic Ovarian Syndrome using patients' clinical data.
20 citations
,
October 2017 in “Clinical Endocrinology” This article reviews existing knowledge on postmenopausal hyperandrogenism and highlights diagnostic challenges, reporting no new clinical results.
20 citations
,
June 2010 in “International Journal of Dermatology” In this study, acne and hirsutism in women were associated with a higher prevalence of polycystic ovary syndrome compared to those without these conditions.
18 citations
,
May 2017 in “Fertility Research and Practice” This study found that increased ovarian volume is associated with markers of insulin resistance in women with polycystic ovary syndrome, while follicle number was not linked to metabolic risk.
13 citations
,
April 2015 in “Human Reproduction” Obese Hispanic women with PCOS are at higher risk for metabolic problems than non-Hispanic white women.
13 citations
,
March 2014 in “Cutaneous and Ocular Toxicology” This study found that while isotretinoin lowered levels of female hormones in patients with severe acne, it did not significantly impact ovarian reserve function.
5 citations
,
May 2019 in “Hormone and Metabolic Research” This study reported that in embryo transfer cycles for women with nonclassic 21-hydroxylase deficiency, dexamethasone use was associated with improved pregnancy rates, and maintaining a BMI below 23.36 kg/m² increased pregnancy probabilities.
4 citations
,
June 2019 in “Revista brasileira de ginecologia e obstetrícia” This article discusses the prevalence of hirsutism in women and highlights that many cases exhibit normal androgen levels, suggesting a need for broader diagnostic approaches.
4 citations
,
September 2018 in “International journal of research - granthaalayah” This study reported that 12% of female Qassim University students had been diagnosed with PCOS, with misconceptions about the condition and treatments observed despite high awareness.
4 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that the FSHR Ser680Asn (rs6166) gene polymorphism is associated with an increased risk of PCOS in the examined population and could serve as a molecular biomarker for identifying risk.
4 citations
,
January 2014 in “Dermatology” This case report details a woman with autoimmune primary ovarian insufficiency linked to hormonal contraception discontinuation, who achieved pregnancy through ovarian stimulation and in vitro fertilization despite typically low fertility in such conditions.
3 citations
,
December 2011 in “Journal of Gynecologic Surgery” In this study, laparoscopic ovarian diathermy with three to five punctures per ovary improved reproductive outcomes for women with clomiphene-resistant polycystic ovary syndrome, while more than six punctures may cause excessive ovarian damage.
2 citations
,
January 2016 in “Journal of Steroids & Hormonal Science” This study found that in PCOS women, polycystic ovarian morphology is linked to more severe hormonal imbalances and insulin resistance, especially in those who are overweight or obese.
1 citations
,
October 2023 in “Egyptian Journal of Immunology” This study found that women with PCOS had significantly higher levels of the pro-inflammatory chemokine MIP-1α compared to controls, suggesting an association with low-grade chronic inflammation, though the increase in MIP-1β levels did not reach statistical significance.
1 citations
,
June 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that N-acetylcysteine was as effective as metformin in improving insulin resistance and metabolic syndrome parameters in women with polycystic ovary syndrome, with fewer side effects.
1 citations
,
September 2015 in “Human Andrology” Married Egyptian women with PCOS have lower sexual desire compared to those without PCOS.
March 2026 in “Journal of Pakistan Association of Dermatologists” This study found that androgenic alopecia is highly prevalent in women with PCOS, suggesting early dermatological screening could help identify related metabolic and psychosocial risks.
In this prospective observational study at a tertiary care center in Uttar Pradesh, researchers observed that comprehensive, individualized treatments significantly improved clinical outcomes for South Asian women with PCOS, including reductions in BMI and improvements in insulin sensitivity, ovulation, and pregnancy rates.
This review explores how technologies like telemedicine, wearable devices, bioengineering, and digital therapeutics are enhancing the management of sexual dysfunction in patients with chronic diseases by offering personalized and accessible solutions, although traditional approaches often fall short.
February 2025 in “Journal of Neonatal Surgery” This study explores the role of antidiabetic medications, particularly metformin, GLP-1 receptor agonists, and DPP-4 inhibitors, in managing PCOS, highlighting their combination with hormonal therapies and lifestyle interventions for a comprehensive treatment approach.
April 2024 in “Indian Scientific Journal Of Research In Engineering And Management” This review discusses the prevalence and contributory factors of polycystic ovarian syndrome and reports no new clinical findings; the authors emphasize the importance of early detection through screening.
March 2024 in “Journal of Rawalpindi Medical College/Journal Rawalpindi Medical College” This study observed that skin conditions like hirsutism, acne, and androgenic alopecia were common in PCOS patients and may aid in its diagnosis.