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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Women with PCOS often have sleep problems, including sleep apnea, which are linked to obesity and depression.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

A thorough skin history and examination are essential for diagnosing and treating skin conditions effectively.

A pregnant woman's skin condition improved after giving birth, possibly due to high estrogen levels during pregnancy.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

The document concludes that diagnosing and treating hair loss is complex and requires understanding its psychological effects and underlying causes, while also calling for more research and new treatments.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Maintaining sexual health after menopause is possible with patient approaches, hormone supplements, and therapy, despite needing more research.

PCOS symptoms can be managed with medication and lifestyle changes.

Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.

Spironolactone may help reduce excessive hair growth in women with high male hormone levels.

New treatments for PCOS are improving fertility and managing symptoms better.

Autoimmune and metabolic issues are linked, and treating one may worsen another.

Most postmenopausal women experience significant skin changes and various skin conditions.

Hair loss after weight loss surgery can improve over time.

Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.

The conclusion is that there's a need for a new conference to establish stricter guidelines for diagnosing Polycystic Ovary Syndrome (PCOS).

PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Baicalin may help reduce excessive male hormone levels in PCOS.

Hirsutism involves excessive hair growth due to hormonal issues and can be treated with medication or surgery.

Hirsutism requires identifying the cause to choose the right treatment, which may include medications like oral contraceptives or dexamethasone.