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Late onset of first period and irregular development of sexual traits in teenage girls can lead to poorer reproductive health.

High levels of androgens during early development may cause PCOS-like symptoms.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Ovulation disorders are a major cause of infertility and menstrual problems in women.

Melatonin implants and long daylight hours alter the timing of hormone release and hair growth in mouflon sheep.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.

Neurosteroids show promise for treating epilepsy and more research is needed.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

Prenatally androgenized ewes can model increased hair diameter in women with PCOS.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.