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Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Scalp cooling reduces chemotherapy-induced hair loss without increasing risk of skin metastases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Docetaxel often causes hair loss, with limited effective treatments and no cure for permanent hair loss.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Fissistigma oldhamii has compounds that help with pain, inflammation, and other health issues.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Pantethine may boost the immune system's ability to fight sarcoma.

Licorice has many health benefits but should be used carefully due to possible side effects.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Scientists successfully made a human growth factor in a plant, which could help with hair growth and bone development.

VB-1, a natural compound, may promote hair growth by enhancing a key cell growth pathway.

Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.