December 2025 in “Journal of Pharma Insights and Research.” This paper reviews the state of knowledge on injectable cryogels, highlighting their unique properties such as shape-memory and mechanical integrity, which allow for minimally invasive delivery via needles and potential applications in oncology and regenerative medicine.
November 2025 in “Molecular and Cellular Biomedical Sciences” This study evaluated the effects of exosome therapy from hypoxia-treated mesenchymal stem cells on a fluconazole-induced alopecia model in rats and found that it significantly reduced TNF-α and increased VEGF levels, suggesting potential as a novel regenerative treatment for alopecia.
September 2025 in “Drug Design Development and Therapy” This study suggests that while platelet-rich products show promise in treating dermatological conditions like chronic wounds and skin aging, there is still a need for standardized methodologies and extensive trials to confirm their long-term clinical benefits.
July 2025 in “International Journal of Allied Medical Sciences and Clinical Research” This review compiles current knowledge of Eclipta prostrata's botanical details, ethnomedical uses, phytochemical components, and various pharmacological activities, emphasizing its potential for modern pharmaceutical formulations based on its anti-inflammatory, antioxidant, anticancer, and other therapeutic properties.
July 2025 in “Journal of medical & health sciences review.” This review highlights the potential of ultrasound-assisted gene therapy for tissue regeneration by improving gene delivery efficiency through techniques like microbubble-mediated sonoporation. The authors discuss its applications in musculoskeletal, cardiovascular, and neural regeneration, while addressing future challenges in optimizing this non-invasive approach for clinical applications.
This study found that MEIS2 expression in neural crest-derived cells is crucial for whisker and trigeminal nerve development in the mesenchyme, indicating an early role in epithelial placode formation and dermal condensation, independent of sensory innervation or Foxd1 expression.
January 2025 in “Journal of Materials Chemistry B”
October 2024 in “SPIRE - Sciences Po Institutional REpository” This study highlights that human hair follicle dermal papilla cells and glypicans play crucial roles in regulating hair follicle stem cell differentiation.
July 2024 in “Bozok Tıp Dergisi” This study found that using a new method to apply platelet-rich plasma during surgery improved early outcomes for patients with hip avascular necrosis, including those with a history of Covid-19.
January 2024 in “GeroScience” This review explores how radiation-induced hair graying can be used as a model to study the mechanisms behind hair graying, focusing on cellular senescence and potential therapeutic targets to address age-related changes. Results are not provided.
January 2024 in “Theranostics” This study found that hypoxia-preconditioned HF-MSC-derived exosomes improved therapeutic outcomes in models of ulcerative colitis, potentially through miR-214-3p-mediated pathways affecting mitochondrial function and inflammatory responses.
January 2024 in “Regenerative Biomaterials” This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.
December 2023 in “Majalah Kedokteran Gigi Indonesia” In this study, cinnamaldehyde loaded onto gypsum-calcium carbonate scaffolds showed promise in promoting early-stage bone healing in rats but was less effective at later stages, with better results when combined with dehydrothermal treatment.
November 2023 in “Frontiers in veterinary science” In this study, researchers used yaks as a natural model to investigate hair growth mechanisms, overcoming previous limitations by establishing in vitro models of hair follicle-associated cells and optimizing methods for cell culture and differentiation.
November 2023 in “Klìtinna ta organna transplantologìâ” This study reviews the regenerative potential and clinical applications of exosomes derived from mesenchymal stem cells in conditions like COVID-19, alopecia, skin aging, and osteoarthritis, highlighting their role as a promising tool in regenerative medicine.
November 2023 in “Linköping University medical dissertations” This research presents a comprehensive workflow for producing EMA-compliant autologous keratinocyte-based therapies for wound healing and explores miRNA-mediated regulations in human keratinocytes and adipose-derived mesenchymal stem cells.
September 2023 in “Frontiers in bioengineering and biotechnology” This review explores the role of JAG1 in disease treatment, highlighting the need for effective methods to deliver JAG1 in its bound form to activate NOTCH signaling for therapeutic applications in craniofacial bone loss and myocardial infarction.
August 2023 in “International journal of medical science and clinical research studies” This review discusses platelet-rich plasma (PRP) therapy for pediatric surgical wound care, evaluating its potential as an adjunctive treatment, but reports no new clinical results.
April 2023 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study concluded that mesenchymal stem cells from adipose tissue harvested using laser-assisted liposuction with selective photo-stimulation are as effective and low-risk for cell therapy as those obtained through conventional liposuction, based on their differentiation potential, cellular proliferation, and cytokine expression.
The study found that adipose-derived mesenchymal stem cells obtained via laser-assisted liposuction with selective photo-stimulation are comparable in differentiation potential and tumorigenic risk to those from conventional liposuction for cell therapy applications.
February 2023 in “Military Medical Science Letters” This study concluded that both pure-PRP and leukocyte-PRP injections significantly reduced serum CD 68 levels in knee osteoarthritis patients, with pure-PRP being more effective than leukocyte-PRP.
March 2022 in “Journal of South Asian Association of Pediatric Dentistry” This case report discusses dental considerations and management strategies for a 7-year-old girl with Ichthyosis Vulgaris; it presents no new clinical results and suggests early preventive therapies.
August 2021 in “Research Square (Research Square)” In this study of clinical-grade ADMSCs, researchers found that cells expanded in PowerStem MSC1 media exhibited increased negative marker expression, chromosomal abnormalities, and signs of senescence compared to those cultured in StemMACS MSC Expansion Media, suggesting that the latter is more suitable for therapeutic applications.
January 2021 in “Medical Research Archives” This study observed that 25-hydroxyvitamin D3 restored rickets symptoms in genetically modified rats, suggesting its direct action through vitamin D receptor pathways.
This article reviews knowledge-sharing efforts in pharmaceutical sciences at the University of Sorocaba, highlighting global collaboration on rational medicine use, without reporting new study results.
This article discusses the Graduate Program in Pharmaceutical Sciences at the University of Sorocaba and emphasizes collaborating internationally to improve health policies and practices but reports no new research findings.
August 2020 in “Research Square (Research Square)” This study found that nanovesicles derived from ReNcell VM cells promoted hair growth in mice by activating the Wnt/β-catenin signaling pathway, suggesting they may serve as an alternative to extracellular vesicles for hair growth therapy.
This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.
May 2020 in “Research Square (Research Square)” This study found that hair follicle stem cells, when transplanted in a rat model of ischaemic stroke, migrated to affected areas, expressed neuron-specific markers, and reduced infarct volume, suggesting potential therapeutic benefits.
November 2019 in “Harper's Textbook of Pediatric Dermatology” This index of Harper's Textbook of Pediatric Dermatology, Fourth Edition, provides no clinical results or new findings.