research Serendipity in Trichology
Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.
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research Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis
The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
research Hirsutism
Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.
research Polycystic Ovary Syndrome: Overview and Management Strategies
The document concludes that managing PCOS involves lifestyle changes, medication for symptoms, and weight loss for fertility improvement.
research Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach
Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.
research Hirsutism
Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.
research Co-Operation Between Follicular Ornithine Decarboxylase and v-Ha-ras Induces Spontaneous Papillomas and Malignant Conversion in Transgenic Skin
High levels of ODC and a mutant Ha-ras gene cause tumors in mice.
research Antizyme Release Is an Early Event in Ornithine Decarboxylase Induction by Hair Plucking
Hair plucking quickly increases antizyme, reducing a specific enzyme activity in rats.
research Modulation of Murine Hair Follicle Function by Alterations in Ornithine Decarboxylase Activity
Ornithine decarboxylase is crucial for hair growth regulation in mice.
research Inhibition of Metastatic Squamous Cell Carcinoma Development in Protein Kinase C Epsilon Transgenic Mice by Alpha-Difluoromethylornithine with Hair Follicle Degeneration and Hair Loss
Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
research Synergy of Eflornithine Cream with Laser and Light-Based Systems for Hair Management
Using Eflornithine cream with laser treatments improves facial hair removal.
research Dynamic Expression of Ornithine Decarboxylase in Hair Growth
Ornithine decarboxylase is crucial for hair growth and follicle development.
research Elevated Ornithine Decarboxylase Activity Promotes Skin Tumorigenesis by Stimulating the Recruitment of Bulge Stem Cells but Not via Toxic Polyamine Catabolic Metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation
Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
research Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis
The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.
research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis
Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Molecular Genetic Dissection of ILVEN Leads to Successful Targeted Therapy
Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.
research Treatment of Androgen Excess in Females: Yesterday, Today, and Tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research Expanding the Phenotype: Four New Cases and Hope for Treatment in Bachmann-Bupp Syndrome
Four new cases of Bachmann-Bupp syndrome suggest potential for targeted treatment.
research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Hair Removal
Current hair removal methods improve appearance but need more research for better options.
research Hair Removal
Electrolysis and laser treatments offer more permanent hair removal, but have limitations.
research Laser Hair Removal: Principles, Techniques, and Advances
Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.
research Androgens and Hair Loss: An In-Depth Analysis of Androgenetic Alopecia
The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.
research Characteristics of Flutamide Action on Prostatic and Testicular Functions in the Rat
Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.
research Cutaneous Application of Alpha-Methylspermidine Activates the Growth of Resting Hair Follicles in Mice
Putting α-methylspermidine on mouse skin can start hair growth.
research CRISPR/Cas9-Based Targeted Genome Editing for Correction of Recessive Dystrophic Epidermolysis Bullosa Using iPS Cells
The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
research Different Polyamine Levels in the Vertex and Occipital Hair of Pattern Hair Loss Patients
People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.
research Specialized Ribosomes in Human Dermal Fibroblast Senescence
Specialized ribosomes affect aging in human skin cells.