71 citations
,
November 2012 in “Expert Opinion on Drug Safety” This article reviews the reported sexual and psychological side effects of 5-alpha reductase inhibitors for benign prostatic hyperplasia, emphasizing the need for further clinical studies.
75 citations
,
January 2014 in “Korean Journal of Urology” This review discusses the adverse effects of 5α-reductase inhibitors, finasteride and dutasteride, on sexual, psychological, and vascular health, emphasizing the need for physicians to inform patients of these risks.
14 citations
,
January 2001 in “Primary Care Update for Ob/gyns” This review discusses the challenges in addressing female sexual dysfunction, focusing on the complexities of female sexual response, levels of dysfunction, clinical identification, and existing treatments, but presents no new clinical findings.
January 2020 in “Fertility and Sterility” This review discusses rare and controversial conditions like painful nocturnal erections and post-finasteride syndrome, calling attention to these issues but providing no new clinical findings.
November 2023 in “L'Endocrinologo” This review examines the impact of polycystic ovary syndrome (PCOS) on women's sexual health, highlighting inconsistencies in existing research; it reports no new results.
55 citations
,
July 1999 in “Clinics in Sports Medicine” This review discusses recent data on the use of anabolic-androgenic steroids and other steroid compounds and reports no new clinical results.
35 citations
,
June 2018 in “Urology” This study of FAERS data suggests that finasteride, particularly at the 1 mg dosage, is associated with a wide range of adverse effects not previously established in long-term studies, especially among younger men.
15 citations
,
November 2015 in “Pharmacopsychiatry” This review discusses sexual dysfunction as a side effect of α-blockers and 5-ARIs for BPH/LUTS, highlighting methodological flaws in existing studies and the need for more rigorous research.
November 2023 in “Frontiers in Neuroendocrinology” This study suggests that post-finasteride syndrome and post-SSRI sexual dysfunction share potential etiopathogenetic mechanisms involving brain modulators, neurotransmitters, and gut microbiota, although more research is needed to understand these conditions fully.
6 citations
,
June 2000 in “Psychiatric Services” This article discusses the sexual health issues faced by postmenopausal women and highlights the need for more research and tailored treatments, but it reports no new clinical results.
October 2015 in “Elsevier eBooks” Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.
12 citations
,
January 2013 in “Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz” Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.
January 2020 in “Archives of urology” This review discusses concerns about persistent side effects of finasteride, such as sexual dysfunction and suicidal ideation, urging the medical community to recognize and address these issues.
3 citations
,
December 2016 in “Sexual medicine reviews” This review discusses methods for improving study design and evaluation in sexual health literature and reports no new clinical results; it highlights current methodological issues and the benefits of validated questionnaires.
April 2015 in “Cambridge University Press eBooks” Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.
21 citations
,
August 2016 in “Translational Andrology and Urology” This review discusses the pathophysiology of delayed ejaculation, highlighting the role of various biogenic and psychogenic factors, but reports no new clinical findings.
3 citations
,
January 2011 in “Female pelvic medicine & reconstructive surgery” This review discusses the impact of hormones on female sexual function and dysfunction, highlighting the complexity and gaps in basic research, and reports no new clinical findings.
31 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.
2 citations
,
March 2004 in “Reviews in Gynaecological Practice” This review discusses treatments for female sexual dysfunction in postmenopausal women, noting that the effectiveness of current pharmaceutical options is inconclusive and emphasizing the importance of individualized care.
November 2024 in “Frontiers in Medicine” In this review, the researchers highlighted the prevalent symptoms in cirrhosis patients, including pain, muscle cramps, sleep disturbances, and mental health issues, and emphasized the need for a comprehensive, multidisciplinary approach for symptom management to improve quality of life.
May 2024 in “Research Square (Research Square)” In this study, impaired sexual function among Iranian women with infertility was linked to higher sexual distress, especially when comorbid PCOS was present, affecting the relationship between sexual pain and distress.
January 2013 in “The Journal of Sexual Medicine” In a rat model, this study found that a hydrogel incorporating adipose-derived stem cells and nerve growth factor may aid in the recovery of erectile function following cavernous nerve injury.
January 2009 in “Springer eBooks” The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.
35 citations
,
January 2012 in “The Journal of Sexual Medicine” This review examines various androgen deprivation therapy methods for advanced prostate cancer, highlighting benefits and potential cardiovascular and sexual adverse effects, but reports no new clinical results.
14 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” This review discusses the fertility and pregnancy challenges faced by women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency and reports no new research findings.
3 citations
,
April 2019 in “Journal of psychosexual health” This review discusses the psychiatric and sexual comorbidities of PCOS, emphasizing the need for a multidisciplinary approach to manage sexual dysfunction due to high prevalence rates found in recent studies.
2 citations
,
October 2022 in “Frontiers in genetics” This case report describes a 46-year-old Italian woman with congenital adrenal hyperplasia who experienced significant improvements in physical and psychological health after receiving a delayed diagnosis and subsequent treatment.
4 citations
,
June 2024 in “BMC Women s Health” This study found that infertile female patients with comorbid PCOS experience increased sexual distress linked to impaired sexual function and heightened sexual pain, indicating a need for further research into related physiological and psychological aspects.
November 2025 in “IntechOpen eBooks” This chapter reviews the complex relationship between PCOS and sexual dysfunction, highlighting its fundamental role as a biopsychosocial manifestation rather than a secondary complication, and calls for comprehensive, patient-centered care; it reports no new clinical results.
June 2024 in “Trends in Urology & Men s Health” This study explores the controversial condition known as post‐finasteride syndrome, observed in some men who experience lasting sexual, neurological, and psychological side effects after stopping finasteride, emphasizing its rarity and the lack of proven treatments.