research Imaging Prostate Cancer With Technetium-99m Tricarbonyl Finasteride Dithiocarbamate
A new compound was effective for imaging prostate cancer in rats.
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research Determination of Rat 5α-Reductase Type 1 Isozyme Activity and Its Inhibition by Novel Steroidal Oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research Synthesis of N-Substituted 3-Oxo-17b-Carboxamide-4-Aza-5a-Androstanes and the Tautomerism of 3-Oxo-4-Aza-5-Androstenes
Researchers made two new compounds that could be used for medicine.
research Optimization of Finasteride Nano-Emulsion Preparation Using Chemometric Approach
Finasteride nano-emulsion optimized using chemometric approach.
research Lack of Association Between Clinical and Biochemical Hyperandrogenism in Patients With Polycystic Ovary Syndrome
Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.
research Improved Forensic Hair Evidence for Drugs of Abuse by Mass Spectrometry
Forensic hair analysis for drugs is now more reliable and accurate.
research Comparison of Mesenchymal Progenitor Cell Coating on MBA and DBM as Biochemical Scaffolds
The demineralized bone matrix scaffold is better for cell attachment than the mineralized bone allograft.
research The Effects of Sodium Metasilicate on Spinal Motoneuron Recovery Following Sciatic Nerve Injury
Sodium metasilicate improved spinal motoneuron recovery after sciatic nerve injury in rats.
research In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome
Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
research Testosterone and Female Sexuality: A Skeptical View
Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.
research Anti-Anginal and Beta-Adrenoceptor Blocking Drugs
Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.
research Distribution Pattern of Some Glycoconjugates in Hair Follicle Regeneration in Rats
Certain sugars increase in some layers of the hair follicle during the middle of the healing process in rats, which may help improve healing.
research Particulate Matter 2.5 Damages Skin Cells by Inducing Oxidative Stress, Subcellular Organelle Dysfunction, and Apoptosis
Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
research Electron Microscope Studies of Hair and Wool
Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research Ancient-Modern Concordance in Ayurvedic Plants: Some Examples
Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.
research Zinc: An Essential Trace Element for Parenteral Nutrition
Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.
research Ozone Interactions with Human Hair: Ozone Uptake Rates and Product Formation
Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Antioxidants in Dermatology
Antioxidants can benefit skin health but should be used carefully to avoid negative effects.
research Mushroom Cosmetics: The Present and Future
Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.
research Scalp Dysesthesia: A Study on Chronic Pain and Itchiness
Antidepressants may improve or resolve scalp dysesthesia in most patients.
research Structural Study of Polymorphs and Solvates of Finasteride
Different forms of hair loss drug can improve effectiveness.
research Design of a Biofluid-Absorbing Bioactive Sandwich-Structured Zn–Si Bioceramic Composite Wound Dressing for Hair Follicle Regeneration and Skin Burn Wound Healing
Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.
research Niosomes as a Vesicular Carrier for Topical Administration of Minoxidil: Formulation and In Vitro Assessment
Niosomes improve minoxidil skin penetration for hair loss treatment.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Chemical Profiling and Quantitation of Bioactive Compounds in Platycladi Cacumen by UPLC-Q-TOF-MS/MS and UPLC-DAD
Researchers identified new compounds in Platycladi Cacumen and found variations in its flavonoid content, which could aid in its quality control.
research Morphological Changes in Human Scalp Hair Roots During Protein Deprivation
Not eating enough protein can cause hair roots to shrink and lose color, and hair to become thinner.
research Formulation and In Vitro Evaluation of Polymeric Enteric Nanoparticles as Dermal Carriers with pH-Dependent Targeting Potential
Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
research Metabolomic Biomarkers in Women with Polycystic Ovary Syndrome: A Pilot Study
Certain metabolites are lower in women with PCOS and could be potential markers for the condition.