134 citations,
July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
17 citations,
January 2020 in “Skin appendage disorders” Certain diets may help with hair growth in people with different types of hair loss.
1 citations,
December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.
March 2023 in “International Journal of Molecular Sciences” The study demonstrates that adipose mesenchymal stromal cell-derived exosomes (ADSC-Exos) carrying miR-122-5p can counteract the inhibitory effects of dihydrotestosterone (DHT) on hair follicles by targeting the TGF-β1/SMAD3 signaling pathway. ADSC-Exos promote hair follicle growth and dermal papilla cell (DPC) proliferation by down-regulating SMAD3, up-regulating β-catenin and versican, and restoring normal hair follicle function. These findings suggest that ADSC-Exos carrying miR-122-5p could be a promising treatment for androgenetic alopecia (AGA).
42 citations,
August 2013 in “International Journal of Women's Health” Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
29 citations,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
17 citations,
November 2021 in “Journal of Cosmetic Dermatology” Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.
16 citations,
March 2021 in “Frontiers in cell and developmental biology” A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
8 citations,
December 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
4 citations,
January 2022 in “Life” Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.
4 citations,
November 2021 in “Cancers” The document concludes that understanding and managing hair loss in cancer patients is important, and more research is needed for better treatments.
3 citations,
January 2021 in “Plastic and Aesthetic Research” Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
3 citations,
August 2020 in “PubMed” Platelet-rich plasma (PRP) is effective in treating various skin conditions and improving hair density, thickness, and patient satisfaction, with lower relapse rates for Alopecia Areata.
2 citations,
January 2017 in “AIMS cell and tissue engineering” Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
1 citations,
January 2021 in “Indian Dermatology Online Journal” The document reviewed the use of platelet-rich plasma (PRP) in treating androgenetic alopecia (AGA), highlighting its potential to stimulate hair growth through various pathways. Despite promising results, the effectiveness of PRP was limited by inconsistent preparation methods and lack of standardization. Meta-analyses of randomized controlled trials (RCTs) showed an increase in hair diameter and count, but results were not statistically significant due to high methodological variability. The manual double-spin method was recommended for PRP preparation, with a platelet concentration of 1 to 1.5 million/μL being optimal. PRP showed better hair growth results compared to finasteride, minoxidil, and low-level laser therapy, and was effective in women unresponsive to minoxidil. The study concluded that PRP should be part of a multipronged approach for treating AGA due to its minimal adverse effects and significant efficacy.
August 2024 in “Stem Cell Research & Therapy” New regenerative therapies show promise for treating hair loss.
May 2023 in “International Journal of Molecular Sciences” Mesenchymal stem cells could help treat radiation-induced bladder damage but more research is needed to overcome current limitations.
24 citations,
November 1992 in “Journal of the American Academy of Dermatology” Early diagnosis and aggressive treatment are crucial for better outcomes in lymphomatoid granulomatosis.
39 citations,
October 2015 in “Case Reports” Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.
29 citations,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
4 citations,
June 2022 in “BioMed Research International” Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.
3 citations,
February 1996 in “Dermatologic Surgery” Walter P. Unger suggests using advanced hair transplant techniques for broader coverage, as they provide natural results and use donor tissue efficiently, while also recommending personalized planning due to the unpredictable progression of baldness.
January 2018 in “Springer eBooks” Lasers are less favored for hair transplant surgery but show promise for hair growth in controlled trials.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
5 citations,
March 2012 in “Actas Dermo-Sifiliográficas” Body-hair transplant successfully improved scarred areas and frontal hair density without visible chest scarring.
20 citations,
May 1992 in “The Journal of Dermatologic Surgery and Oncology” Dr. Norwood's analysis highlights the need for careful patient selection and strategic hair transplant design to create a natural-looking hair density.
24 citations,
May 2021 in “Nature Communications” Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
1 citations,
July 2018 in “Elsevier eBooks” FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
February 2018 in “InTech eBooks” PRP therapy is effective for hair regrowth and improving hair quality with minimal side effects.