119 citations,
November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
101 citations,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
75 citations,
October 2012 in “Journal of Investigative Dermatology” Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
69 citations,
December 2015 in “BMC plant biology” Three genes in Arabidopsis are important for plant growth and development by affecting sugar attachment to proteins.
65 citations,
June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
40 citations,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
33 citations,
May 2006 in “Journal of Investigative Dermatology” PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
11 citations,
July 2020 in “Scientific Reports” Statins may be linked to reproductive organ conditions, and their risks should be monitored.
11 citations,
February 2004 in “Clinical and Experimental Ophthalmology” Taking Propecia might lead to the development of cataracts.
9 citations,
February 2018 in “Journal of Patient-Reported Outcomes” New tools were created to help lupus patients report their symptoms and impacts more accurately.
6 citations,
October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
5 citations,
January 2017 in “Endocrinology” Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
4 citations,
November 2021 in “Biomedicines” New digital tools are improving the diagnosis and understanding of irreversible hair loss conditions.
3 citations,
April 2019 in “Annals of hepatology” Peanut allergies can be transferred through organ transplants.
2 citations,
February 2024 in “Nature cell biology” Mechanical forces are crucial for shaping cells and forming tissues during development.
2 citations,
March 2019 in “PubMed” A new tool helps lupus patients and doctors better track symptoms and quality of life.
1 citations,
October 2022 in “Biomedicines” Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
1 citations,
July 2015 in “Cytokine” Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
April 2023 in “Journal of Investigative Dermatology” Being allergic to linalool, a common fragrance ingredient, might contribute to developing frontal fibrosing alopecia.
Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.
258 citations,
July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
171 citations,
October 1990 in “Alcoholism/Alcoholism, clinical and experimental research” The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
146 citations,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
124 citations,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
63 citations,
May 2015 in “PloS one” GALT5 and GALT2 are important for plant growth and development because they help with protein glycosylation.
28 citations,
May 2020 in “BMC plant biology” The study concluded that three enzymes are important for plant development by affecting sugar composition and calcium binding in plants.
25 citations,
March 2022 in “International journal of biological macromolecules” miR-181a-5p helps hair growth by activating a specific signaling pathway.
15 citations,
January 2014 in “BioMed Research International” Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
14 citations,
April 2017 in “American Journal of Transplantation” Skin problems from transplant drugs are common and need careful management in organ transplant patients.