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PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Cleanroom workers in a battery factory have worse skin and eye conditions due to the very dry environment.

The document reviews key historical figures and discoveries in dermatology.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.

Some drugs can cause serious side effects like heart issues and nervous system problems, but certain drugs for Parkinson's and overactive bladder may be safer, though they still have some common side effects.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.