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Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.

Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.

Minoxidil effectively treats severe hypertension but has notable side effects.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

ADAM17 could be a potential target for treating PCOS.

Women with PCOS are at higher risk for gum disease, and managing shared risk factors can help both conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Skin problems are common and important signs of eating disorders and treating the eating disorder can improve these skin conditions.

Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.

Hirsutism causes significant psychological distress in women.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Skin and nail problems like hair loss, dry skin, and fungal infections are common in people with long-term Type 2 Diabetes and can be prevented with good blood sugar control and foot care.

Biologics for severe asthma have known side effects, but some new risks need more study.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Using combined treatments can help manage acne by targeting the bacteria and skin changes that cause it.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.