research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
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research Rabson-Mendenhall Syndrome: Two Case Reports and a Brief Review of the Literature
The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.
research Management of Recurrent Ischemic Priapism: A Complex Condition with Devastating Consequences
Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.
research Optimization of Microstructured Biodegradable Finasteride Formulation for Depot Parenteral Application
Improved finasteride formula allows slow, sustained release and better absorption for patients.
research Systemic Therapy of Androgenic Alopecia
The document doesn't provide enough information to summarize.
research Regulation of the Human Hair Cycle
The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.
research Shock Waves for Hair Growth and Regeneration in Patients with Female Pattern Hair Loss
Extracorporeal shock waves significantly improve hair growth in women with female pattern hair loss.
research The Use of Photodynamic Therapy for Treatment of Acne Vulgaris
Photodynamic Therapy is an effective treatment for mild to severe acne.
research Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome: A Six-Month, Open-Label Randomized Study
Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
research Abstracts
Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.
research Intracrinology and the Skin
DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
research Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Phospholipid-Polymer Hybrid Nanoparticle-Mediated Transfollicular Delivery of Quercetin: Prospective Implementation for the Treatment of Androgenic Alopecia
Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.
research Female Hyperandrogenism
The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.
research RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia, and Hirsutism
RU 58841 may treat acne, hair loss, and excessive hair growth.
research Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
Finasteride shows promise for female hair loss, but more research needed.
research Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders
New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
research Incidence of Alopecia from Endocrine Therapies in Cancer
Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.
research The Potential Role of Minoxidil in the Hair Transplantation Setting
Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.
research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome
The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
research Hirsutism
Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.
research FCE 28260, A New 5α-Reductase Inhibitor: In Vitro and In Vivo Effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts
Common skin conditions can greatly affect a person's mental health and social life.
research Agaricus Subrufescens Ameliorates Ovarian Dysfunction and Regulates Altered Biochemical Parameters in Rats with Letrozole-Induced Polycystic Ovarian Syndrome
Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Innovative Approach for Polycystic Ovary Syndrome Treatment: Brown Adipose Tissue
Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
research Finasteride
Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.