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The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

A woman had severe reactions to methotrexate, including skin issues and organ problems, but improved after 38 days in the hospital.

Hair loss can be an early sign of HIV infection.

Birth control pills can cause skin issues but may help with acne and hirsutism, and choosing the right type can minimize side effects.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.

Topical minoxidil and oral finasteride and dutasteride are the most effective treatments for male and female pattern hair loss, but study quality varies.

Baricitinib at 2mg and 4mg doses improved work productivity and reduced costs for adults with atopic dermatitis.

Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.

Methotrexate is effective for treating rheumatoid arthritis but requires regular monitoring.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.

Zinc is effective for treating various skin conditions, including warts and acne.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Current treatments for alopecia show no significant long-term benefits.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Oxidative stress contributes to hair graying and loss as we age.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.