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A 5-mg dose of oral minoxidil slightly lowers blood pressure temporarily, especially in those with higher initial blood pressure.

Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.

Higher doses of isotretinoin may lead to more hair loss.

Sublingual minoxidil safely promotes hair growth.

Minoxidil is effective for hair growth and safe for long-term use.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.

The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.

9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.

A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Levetiracetam often causes behavioral issues, while oxcarbazepine is more likely to cause sleepiness in epilepsy patients.

Tridax procumbens plant parts boost immune response in mice.

Microsponges delivery system is a safe, versatile method for controlled drug release in various treatments.

LAAM caused developmental toxicity in tolerant rats without causing birth defects.

Finasteride causes harmful organ changes in female mice.