169 citations,
August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
29 citations,
July 2012 in “Fertility and Sterility” Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.
25 citations,
September 1977 in “Journal of Toxicology and Environmental Health” High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Low-dose isotretinoin is as effective as conventional doses for acne and has fewer side effects.
Flutamide effectively treats female pattern hair loss long-term with low doses being safe for the liver.
23 citations,
January 2018 in “International Journal of Dermatology” Oral isotretinoin, especially at higher doses for at least 3 months, is effective for treating folliculitis decalvans.
5 citations,
January 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil is an effective and safe treatment for hair loss.
September 2023 in “Food and chemical toxicology” High doses of some selenium supplements caused liver and reproductive harm in rats.
Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).
June 2023 in “Journal of Cosmetic Dermatology” Finasteride 5mg daily is the most effective for female pattern hair loss, with higher doses of treatments generally more effective.
24 citations,
September 2019 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil improved or stabilized hair loss in some patients, but higher doses may be needed for significant effects.
22 citations,
January 1979 in “JAMA” Minoxidil can lower blood pressure effectively and safely in emergencies.
14 citations,
June 2009 in “Journal of veterinary internal medicine” High doses of albendazole can be deadly for alpacas.
November 2023 in “Current Dermatology Reports” Oral minoxidil is effective for various hair loss types and may improve male sexual function, but aspirin can reduce its effectiveness.
15 citations,
May 2011 in “Veterinary Dermatology” Vitamin A might be a safe extra treatment for dogs with sebaceous adenitis, but more research is needed to prove its effectiveness.
79 citations,
September 2018 in “Dermatologic therapy” Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.
November 2023 in “Food science of animal resources” Lactilactobacillus curvatus LB-P9 taken orally helps hair regrow faster and thicker in mice.
52 citations,
September 1996 in “Obstetrics & Gynecology” People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.
20 citations,
March 1994 in “Clinical and Experimental Dermatology” Too much topical minoxidil can cause excessive hair growth, but stopping treatment reverses it.
3 citations,
October 2009 in “Iranian Journal of Basic Medical Sciences” Buxus wallichiana extract improves hair growth and has antioxidant properties, with oral use more effective than topical.
1 citations,
March 2023 in “Medicine” Satoyoshi syndrome can cause eye problems like uveitis and retinal vein issues.
3 citations,
May 2022 in “Journal of The American Academy of Dermatology” The conclusion is that 24 weeks of low-dose oral minoxidil is safe for men with hair loss, with no significant changes in heart rate or blood pressure.
research Acne
81 citations,
January 2002 in “American journal of clinical dermatology” Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
58 citations,
November 2000 in “Journal of the American Veterinary Medical Association” Lufenuron effectively and quickly treats fungal infections in dogs and cats without side effects.
30 citations,
January 1998 in “Dermatology” Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.
18 citations,
July 1975 in “Clinical Pharmacology & Therapeutics” Oral minoxidil effectively controls blood pressure quickly and safely.
1 citations,
June 2017 in “Journal of the American Academy of Dermatology” Oral tofacitinib may be an effective and tolerable treatment for some people with severe alopecia areata.
22 citations,
January 2002 in “Treatments in endocrinology” Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
1 citations,
January 2020 in “Surgical & Cosmetic Dermatology” Combining oral minoxidil with JAK inhibitors helps regrow hair in severe alopecia areata cases.
19 citations,
May 2020 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil improves hair growth in male hair loss.