52 citations
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August 1993 in “Clinical endocrinology” This study found that intravenous high dose calcium infusions followed by high dose oral calcium effectively treated vitamin D dependent rickets type II, leading to complete biochemical and radiological healing and improved growth in two patients.
October 1990 in “Pediatric Research” This case report details a severe instance of VDR-II where intravenous calcium infusions, administered nightly, successfully improved clinical, radiological, and biochemical signs of rickets without alopecia despite ineffective calcitriol therapy.
1 citations
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January 2018 in “Journal of Steroids & Hormonal Science” This study observed no significant difference in vitamin D levels between children with alopecia areata and controls, but higher complete improvement in alopecia was noted among patients with vitamin D deficiency undergoing oral vitamin D treatment.
March 1995 in “Proceedings of the British Society of Animal Science” This review discusses zinc's role in dog metabolism and suggests that zinc from amino acid chelates might be better absorbed than from inorganic sources, but reports no new experimental results.
March 1995 in “Proceedings of the British Society of Animal Science” This review discusses zinc's role in dog nutrition, emphasizing that zinc absorption may be improved when provided as an amino acid chelate rather than an inorganic source, but reports no new results.
10 citations
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January 2014 in “Journal of Pediatric Endocrinology and Metabolism” This study identified three new mutations in the VDR ligand-binding domain that may cause dysfunction, and noted that oral calcium and calcidol treatment was effective, but only one patient experienced hair growth.
1 citations
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January 2016 in “Journal of Nepal Paediatric Society” This case report discusses a 27-month-old girl with vitamin D-dependent rickets type II, who showed minor improvement in skeletal features and alopecia after high-dose oral calcium and vitamin D3 treatment.
August 2019 in “International journal of contemporary pediatrics” This case study reports that a 3 ½ year-old male with vitamin D-dependent type II rickets showed partial improvement in alopecia and rickets when treated with high doses of 1,25(OH)2 vitamin D3.
July 2023 in “Journal of medical and health studies” This case study reported on a 3-year-old child with vitamin D-dependent rickets type II treated in the Gaza Strip, whose condition deteriorated despite vitamin D and calcium treatments, leading to recurrent chest infections, respiratory failure, and eventual death.
15 citations
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July 2015 in “Developmental Dynamics” This study highlights the role of Orai1 in ameloblast differentiation and maturation, showing that its down-regulation affects cell proliferation and enamel formation during tooth development.
18 citations
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November 2009 in “Calcified tissue international” A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.
2 citations
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April 2019 in “Медицинский совет” This article reviews the problem of acne and hirsutism in women, highlighting the effectiveness of combined oral contraceptives containing drospirenone and levomefolate calcium in managing these conditions and polycystic ovary syndrome, but no new clinical results are reported.
February 2024 in “Journal of Education, Health and Sport” This review discusses current pharmacological and non-pharmacological treatment strategies for PCOS, emphasizing the need for a personalized, multimodal approach due to incomplete understanding of the syndrome's pathogenesis.
4 citations
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November 1981 in “Indian Journal of Dermatology Venereology and Leprology” This study observed that oral calcium pantothenate may reverse hair greying in some adolescent cases, as seen in two girls whose grey hairs turned black after treatment.
11 citations
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August 1948 in “Journal of Investigative Dermatology” In this study, oral calcium pantothenate was associated with improvement in the inflammatory phase of discoid lupus erythematosus of the scalp, with the most marked response observed in subacute cases.
January 2025 in “Clinical Pediatric Endocrinology” In a case study of vitamin D-dependent rickets type 2A, researchers observed that while active vitamin D treatment failed to improve bone and laboratory abnormalities, oral calcium lactate significantly ameliorated these issues, although skin and hair problems remained unresponsive.
2 citations
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August 2020 in “Clinical, Cosmetic and Investigational Dermatology” This study found that a combination of oral compounds improved metabolic activity, cell viability, and proliferation in hair follicular keratinocytes, with L-cystine playing a key role in protection against oxidative stress.
October 2011 in “Journal of dermatology” A man with a rare skin condition and a new gene mutation developed high calcium levels due to his treatment.
7 citations
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June 2016 in “Bone Research” In this study, a Chinese Han family with hereditary vitamin D-resistant rickets was found to have a homozygous missense mutation in the VDR gene, and the affected individual uniquely responded well to treatment with oral calcium and low-dose calcitriol.
January 1988 in “Chemical and Pharmaceutical Bulletin” This study found that ointments containing indomethacin and its calcium salt showed potent anti-inflammatory effects on rat paw edema and arthritis with minimal skin irritation, suggesting potential for clinical use.
1 citations
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May 2019 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” In this study, a novel VDR gene mutation was identified in a child with HVDRR, and the researchers observed that high-dose intravenous calcium therapy led to significant and sustained improvement in rickets symptoms.
8 citations
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January 1984 in “Veterinary Pathology” This study found no conclusive link between prolonged mibolerone treatment and perifollicular mineralization in toy poodles, suggesting it may instead be a senile change common in the breed.
April 2024 in “Research Square (Research Square)” This case report describes a 27-year-old male with autoimmune polyglandular syndrome type 1, characterized by symptoms including fever, dysarthria, dysphagia, oral candidiasis, nail dystrophy, alopecia, hypoparathyroidism, and dilated cardiomyopathy. The study highlights unique bilateral symmetrical brain calcifications and underscores the syndrome’s diverse manifestations.
January 2023 in “International Journal of Contemporary Pediatrics” This case study describes a 5-year-old boy with vitamin D dependent rickets type 2, motor delays, and alopecia totalis who showed improved biochemical parameters with calcium and calcitriol treatment.
December 2014 in “Endocrinología y nutrición” The woman's rare combination of diseases suggests an unknown factor may predispose individuals to multiple endocrine diseases.
January 2023 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This source explores treatments for male-pattern baldness, highlighting finasteride, which reduces DHT levels to support hair growth, and minoxidil, used for vasodilation and hair health, though the exact mechanisms remain partly unclear.
30 citations
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October 2009 in “Journal of Veterinary Internal Medicine” This report describes a unique case of hereditary vitamin D-resistant rickets (HVDRR) in a dog, caused by a VDR gene mutation resulting in severe hypocalcemia and bone issues, which presented with symptoms similar to those observed in humans.
July 2018 in “International journal of clinical & experimental dermatology” This narrative review describes the components of human hair and their nutritional importance but reports no clinical results; the authors suggest dietary sulfur amino acids are essential for hair health.
Taking calcium may help elderly with osteoporosis, birth control with levonorgestrel doesn't increase heart attack risk, Salmonella can cause arthritis, a national ethics committee is recommended, and sulfasalazine might help with a hair loss condition.
61 citations
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September 1970 in “Journal of the American Geriatrics Society” In this study, anabolic and catatoxic steroids were reported to prevent weight loss, tissue calcification, and cardiac necrosis in a rat model of disturbed calcium metabolism and progeria-like syndrome.