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The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Different types of skin cells play specific roles in development, healing, and cancer.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Some medicinal plants can help heal wounds and may lead to new treatments.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Blocking JAK-STAT signaling can lead to hair growth.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Tofacitinib may help treat severe hair loss, but more research is needed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Liposomes could improve how skin care products work but are costly and not very stable.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Lower SHBG levels may increase the risk of PCOS.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Some common medications can harm male fertility, but many effects can be reversed.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.