2 citations
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September 2021 in “JAAD case reports” This report describes a case of a woman with ophiasis-pattern alopecia areata who experienced significant hair regrowth and maintained it for 6 months after treatment with dupilumab, though she eventually relapsed.
January 2026 in “Saudi Journal of Internal Medicine” This narrative review suggests that while corticosteroids and Janus kinase inhibitors may be effective for treating ophiasis-pattern alopecia areata in both adults and children, the limited age-specific evidence underscores the need for further research to confirm their efficacy and safety across age groups.
July 2024 in “Clinical Case Reports” This study suggests that young females may experience a rare coexistence of Frontal Fibrosing Alopecia and ophiasis pattern Alopecia Areata, possibly sharing a common underlying pathophysiology.
December 2023 in “JEADV Clinical Practice” In this report, a young Caucasian woman developed a hairy tongue as an unusual side effect during baricitinib therapy for severe alopecia areata, which was managed by daily toothbrush debridement.
September 2023 in “Cureus” This case report describes a four-month-old infant with atypical alopecia areata following a cultural head-shaving ritual, who showed improvement with topical triamcinolone treatment, though not full symptom resolution, highlighting the rarity and complexity of managing AA in infants.
November 2025 in “International Journal of Research in Medical Sciences” In this case study, the authors explored the management of ophiasis, a rare and challenging form of alopecia areata, in a 3-year-old boy using the Unani system of medicine, aiming to provide insights for treatment approaches.
This case report describes a 21-year-old man with alopecia areata presenting as a U-shaped hair loss pattern resembling Hamilton grade VII male-pattern baldness, with no signs of inflammation or related conditions.
January 2014 in “International Journal of Trichology” A man had an unusual type of hair loss that didn't match known patterns and didn't improve with treatment.
11 citations
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October 2018 in “Pediatric dermatology” In this case report, the authors describe a child with treatment-resistant alopecia areata who successfully responded to leflunomide and anthralin, proposing this combination as a potentially cost-effective alternative for managing recalcitrant cases by possibly inhibiting the JAK/STAT pathway.
3 citations
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November 2016 in “Clinical Pediatrics” A girl with Crohn's disease developed hair loss from her medication, which improved with treatment but later returned.
January 2021 in “International journal of dermatology, venereology and leprosy sciences” This study found that, among 100 patients with alopecia areata, the most prevalent subtype was patchy alopecia areata, with characteristic trichoscopic features including black dots, yellow dots, and empty hair follicles.
1 citations
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October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that low serum ferritin levels in pediatric patients with alopecia areata were associated with increased disease severity and longer duration.
This chapter reviews alopecia areata treatments, highlighting factors like age and disease extent in choosing management strategies, but reports no new clinical findings.
January 2016 in “Journal of The Korean Medical Association” This paper discusses alopecia areata, its autoimmune nature, factors influencing susceptibility, diagnostic challenges, and treatment limitations, concluding that no current therapy is curative or preventive; it reports no new clinical results.
July 2025 in “SKIN The Journal of Cutaneous Medicine” In this study, a patient with severe alopecia areata showed significant hair regrowth after 15 months of partial response to baricitinib and oral minoxidil, following the addition of dupilumab to their treatment regimen.
July 2025 in “Dermatology Reports” This report presents a rare case of discoid lupus erythematosus in a Saudi woman, highlighting the need for dermatologists to recognize atypical presentations to prevent misdiagnosis and treatment delays.
13 citations
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November 2012 in “Journal of The European Academy of Dermatology and Venereology” This study found that topical clobetasol propionate cream provided a modest improvement in hair regrowth for alopecia areata patients, though those with atopy had higher relapse rates after treatment completion.
1 citations
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April 2020 in “Baylor University Medical Center Proceedings” This case report describes a 58-year-old man with ophiasis-pattern alopecia areata who showed significant hair regrowth after treatment with clobetasol and microneedling with triamcinolone.
October 2025 in “International Journal of Risk & Safety in Medicine” In this case study, a 5-year-old girl with alopecia areata and atopic dermatitis that were unresponsive to previous treatments achieved substantial improvement with long-term tofacitinib, highlighting its potential safety and efficacy in managing both conditions concurrently.
August 2024 in “Skin Appendage Disorders” This study introduces "alopecia areata in a male or female pattern distribution" as a new clinical subtype of alopecia areata, observed in three adult cases, to enhance diagnostic precision and treatment personalization.
15 citations
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October 1996 in “Archives of Dermatology” This review of alopecia areata cases at Virgen Macarena University Hospital identified a new hair regrowth pattern they term "androgenetic alopecia type" and described a unique inverse form called "sisaipho type" in three cases.
February 2024 in “Curēus” In this case report, secukinumab therapy for spondyloarthritis was associated with the development of alopecia areata in a 46-year-old woman, which improved after discontinuing the medication.
May 2023 in “Authorea (Authorea)” In this report, researchers documented a rare complication linked to levofloxacin, used as a second-line treatment for tuberculosis, which could include various adverse events during TB therapy.
3 citations
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December 2018 in “Journal of Pakistan Association of Dermatology” This study found that patients with alopecia areata often presented with multilocular patches, common scalp involvement, and associated conditions like atopic dermatitis; the disease predominantly affected younger individuals.
1 citations
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March 2020 in “Australasian Journal of Dermatology” This report describes five cases of bitemporal alopecia areata with frontal hairline involvement, detailing their management strategies and highlighting potential differential diagnoses, but does not present new clinical results.
February 2026 in “Journal of the American Academy of Dermatology” In this study, researchers characterized the clinical features of ophiasis, an uncommon type of alopecia areata, and proposed a new subtype classification that may help predict treatment response and guide management, noting that ophiasis generally has a chronic and refractory nature.
1 citations
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November 2024 in “Archives of Dermatological Research” The authors discuss that hair loss affecting the occipital scalp is understudied and may be caused by factors like movement irritation and clothing occlusion; this lack of data can lead to missed diagnoses and inadequate treatment.
December 2023 in “EPRA international journal of multidisciplinary research” In this review, researchers examined current knowledge on alopecia areata, finding it affects approximately 2% of individuals, with a likely autoimmune and genetic basis, and highlighting its association with other medical and psychiatric conditions, although no cure currently exists.
July 2025 in “Journal of Dermatology Research Reviews & Reports” In this case study, a 10-year-old girl with infantile ophiastic alopecia areata and ciliary madarosis showed excellent hair and eyelash regrowth after 56 days of treatment involving oral corticosteroids, topical minoxidil, and clobetasol hair lotion, following an initial diagnosis and psychological evaluation.
7 citations
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October 2022 in “Advances in Therapy” This review of real-world treatment options for AA indicates that current therapies are insufficient, with high dissatisfaction rates, highlighting a need for improved solutions.