February 2026 in “Journal of the American Academy of Dermatology” In this study, researchers characterized the clinical features of ophiasis, an uncommon type of alopecia areata, and proposed a new subtype classification that may help predict treatment response and guide management, noting that ophiasis generally has a chronic and refractory nature.
This chapter reviews alopecia areata treatments, highlighting factors like age and disease extent in choosing management strategies, but reports no new clinical findings.
13 citations
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November 2012 in “Journal of The European Academy of Dermatology and Venereology” This study found that topical clobetasol propionate cream provided a modest improvement in hair regrowth for alopecia areata patients, though those with atopy had higher relapse rates after treatment completion.
13 citations
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September 2018 in “Journal of the American Academy of Dermatology” This editorial proposes a new classification for alopecia areata that incorporates the SALT score and body hair involvement, aiming to improve the assessment and treatment outcomes.
January 2021 in “International journal of dermatology, venereology and leprosy sciences” This study found that, among 100 patients with alopecia areata, the most prevalent subtype was patchy alopecia areata, with characteristic trichoscopic features including black dots, yellow dots, and empty hair follicles.
3 citations
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December 2018 in “Journal of Pakistan Association of Dermatology” This study found that patients with alopecia areata often presented with multilocular patches, common scalp involvement, and associated conditions like atopic dermatitis; the disease predominantly affected younger individuals.
1 citations
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October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that low serum ferritin levels in pediatric patients with alopecia areata were associated with increased disease severity and longer duration.
February 2026 in “International Journal of Clinical Dermatology” In this retrospective study, researchers observed that alopecia areata manifests in various forms among Malagasy children and presents challenges in treatment, with mixed regrowth results following corticosteroid therapy and methotrexate.
January 2014 in “International Journal of Trichology” A man had an unusual type of hair loss that didn't match known patterns and didn't improve with treatment.
June 2024 in “Bioscientia Medicina Journal of Biomedicine and Translational Research” In this study, researchers observed that among pediatric alopecia areata patients at Dr. M. Djamil General Hospital Padang, patchy alopecia was most common, affecting 80% of cases, with frequent trichoscopic features including yellow dots, black dots, and broken hairs.
30 citations
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August 2015 in “JAAD case reports” This case report describes a patient with corticosteroid-resistant ophiasis alopecia areata who experienced prompt hair regrowth after receiving platelet-rich plasma injections.
1 citations
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April 2020 in “Baylor University Medical Center Proceedings” This case report describes a 58-year-old man with ophiasis-pattern alopecia areata who showed significant hair regrowth after treatment with clobetasol and microneedling with triamcinolone.
September 2023 in “Cureus” This case report describes a four-month-old infant with atypical alopecia areata following a cultural head-shaving ritual, who showed improvement with topical triamcinolone treatment, though not full symptom resolution, highlighting the rarity and complexity of managing AA in infants.
April 2024 in “Dermatology and therapy” This study surveyed dermatologists in Greece and Italy and found significant variability and challenges in the diagnosis and treatment of alopecia areata, including limited use of severity scores and diverse treatment approaches, particularly for special site involvement and chronic cases.
18 citations
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June 2017 in “Journal of The American Academy of Dermatology” In this study, trichoscopy consistently identified typical findings of frontal fibrosing alopecia, revealing three unusual clinical patterns in 18.4% of patients, which may aid in the differential diagnosis when clinical presentations are atypical.
36 citations
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January 2015 in “Dermatology” In this study, bimatoprost solution showed better results than corticosteroid in terms of rapidity, percentage of hair regrowth, and side effects for treating scalp alopecia areata.
13 citations
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June 2010 in “Journal of dermatological treatment” This study found that diphencyprone showed a significant clinical response for treating alopecia areata, while tacrolimus was not effective.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Alopecia areata is a hair loss condition that often starts before age 30 and can affect various body parts, with unpredictable hair regrowth chances.
July 2023 in “The Egyptian Journal of Hospital Medicine ” This review discusses the pathophysiology of alopecia areata, highlighting the role of CD8 cytotoxic T cells and the upregulation of JAK signaling pathways; it reports no new experimental results.
222 citations
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September 2016 in “JCI insight” This research overview highlights that although JAK inhibitors show promise as potential treatments for alopecia areata based on recent insights into the disease mechanism, their efficacy has not yet been thoroughly evaluated in a systematic manner.
45 citations
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January 2010 in “International journal of trichology” This review examines topical immunotherapy for severe alopecia areata, noting that diphencyprone and squaric acid dibutylester are non-mutagenic options with similar efficacy but different practical considerations, and reports no new clinical results.
13 citations
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December 2001 in “Dermatologic therapy” This review discusses the clinical presentations of alopecia areata, introduces guidelines for treatment studies, and explores potential changes in cutaneous innervation, but reports no new clinical results.
January 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” In this study, both fractional carbon dioxide laser therapy and cryotherapy were found to be effective and safe for treating patchy alopecia areata, showing similar efficacy in improving hair growth compared to untreated control patches.
2 citations
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January 2020 in “Skin appendage disorders” This study in Mexican patients with alopecia areata found that body hair involvement was linked to disease progression, while treatment adherence was associated with both remission and progression.
1 citations
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May 2017 in “Journal of The American Academy of Dermatology” In this study, increasing cases of allergic contact dermatitis in Bulgaria were linked to the use of natural products like propolis and marigold.
September 2025 in “Diseases” This study found that patients with patchy alopecia areata had significantly higher serum levels of pro-inflammatory cytokines IL-6, TNF-α, IL-17A, and IL-21 compared to healthy controls, with these levels correlating positively with disease severity, age, and disease duration.
May 2017 in “Journal of The American Academy of Dermatology” This study reported an increase in allergic contact dermatitis cases linked to natural products, particularly propolis and marigold, with a higher incidence in women than men.
1 citations
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June 2024 in “Cosmoderma” Most patients with alopecia areata in Syria are young adult males, often with patchy scalp hair loss.
12 citations
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September 2020 in “Journal of cosmetic dermatology” This study found that trichoscopy aided in assessing treatment responses for patchy alopecia areata, with both intralesional corticosteroids and platelet-rich plasma showing effectiveness, but only PRP significantly improved patient symptom impact scores.
April 2023 in “Journal of Cosmetic Dermatology” This case-control study observed that individuals with alopecia universalis and patchy alopecia areata had a higher frequency of fatty liver compared to controls, though the differences were not statistically significant.