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Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

Different amounts of daylight affect cashmere growth in goats by changing the activity of certain genes and molecules.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Activated ras can protect kidney cells from a certain substance that causes cell death.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.