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This study by Flores and colleagues found that the type of tumor that develops in a specific subset of epidermal stem cells is influenced by which tumor suppressor gene is deleted.

This review explores the complex, context-dependent roles of tumor-secreted proteins and suggests that some proteins traditionally seen as tumor-promotive may act as tumor-suppressors in different environments, emphasizing the influence of cell fitness and treatment exposure.

Immune cells boost stem cell activity in hairy moles, causing more hair growth.

This study suggests that over-expression of Sp2 may limit stem cell differentiation and contribute to tumorigenic cell growth in mice.

This study demonstrates that melanocyte stem cells can be a source of melanoma in a mouse model, resembling human melanoma in both heterogeneity and gene signatures.

This study suggests that p63 is consistently expressed in the basal cells of the skin and may influence differentiation and the development of common skin carcinomas.

This review discusses how increased gene copy number for telomerase components may contribute to telomerase up-regulation in cancer cells, although the exact mechanisms are not fully understood.

This study presents iSiMPRe, a method identifying protein regions enriched in mutations, revealing potential cancer-related genes and enhancing understanding of mutation effects across a wide range of cancer types.

This review discusses recent advances in understanding Merkel cell carcinoma biology, including the development of genetically-engineered mouse models and potential therapeutic targets, but reports no new clinical results.

This article reviews the evolving understanding of hematopoietic stem cells, including their heterogeneity and the role of cytokines in lineage determination, and reports no new results.

This case study in a renal transplant patient observed that eruptive KA-type SCCs exhibited aggressive behavior and genetic expression changes following intralesional chemotherapy, indicating potential caution against routine use of such treatments in similar cases.

This review synthesizes current evidence on the Warburg effect in anaplastic thyroid carcinoma and discusses potential therapeutic targets, but reports no new clinical results.

This review suggests that the TSC22D family genes may influence metabolism and cancer, potentially serving as a therapeutic target for conditions like diabetes, obesity, and certain tumors, depending on the tumor environment.

This study suggests that while cellular senescence impairs epidermal stem cells in aging, it also serves an essential role during embryonic development, highlighting its dual functional nature.

This study found that MYH9 acts as a tumor suppressor in squamous cell carcinomas by stabilizing p53 in the nucleus, suggesting its role in cancer prevention.

This study observed that activating Wnt signaling pathways increased the efficiency of reprogramming human fibroblasts into induced pluripotent stem cells compared to untreated cells.

Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.

This review discusses the role of the hedgehog signaling pathway in hematological cancers and its potential as a therapeutic target; it reports no new clinical findings.

This study found a rare germline mutation in the Birt–Hogg–Dubé gene in a Japanese patient with renal cell carcinoma, suggesting distinct biological features and challenging current renal tumor classifications.

This study found that overexpression of betacellulin in transgenic mice delayed hair follicle morphogenesis and cycling, increased keratinocyte proliferation, and enhanced wound angiogenesis without affecting wound healing strength.

This review discusses the expanded understanding of WNT10B's role in various tissues and diseases over the past decade, emphasizing its genetic correlations and potential therapeutic implications, but reports no new clinical results.

Male infertility and genitourinary birth defects are often linked to genetic issues.

This study suggests that BRAF inhibitors, particularly Encorafenib and Dabrafenib, may have potential applications in wound healing by targeting specific proteins involved in the healing process in murine models.

In this study, researchers used a network pharmacology approach to highlight significant interactions between compounds in rosemary (Salvia rosmarinus) and genes related to functional dyspepsia, suggesting potential pathways for developing treatments against gastrointestinal diseases.

This review discusses two approaches to address aging: a tactical method to delay and slow age-related issues, and a strategic method aiming to eliminate aging altogether by targeting its root cause.

New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.

This review examines the dermatologic effects of tobacco use and nicotine, noting potential benefits and drawbacks for various skin conditions, but reports no new clinical results.

This study found that activating CXCR2 on ras-transformed keratinocytes promotes migration and tumor development in a mouse skin model.

This article reviews the role of microRNAs in skin-related conditions like psoriasis and wound healing and highlights their potential as therapeutic targets and diagnostic biomarkers, without reporting new experimental results.

This review discusses various types of stem cells used in regenerative medicine, including adult stem cells and induced pluripotent stem cells (iPSCs), and evaluates them based on their embryonic tissue origins to explore new therapeutic approaches.