Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review examines the antitumor effects of metformin and highlights discrepancies between basic and clinical study results, noting that these may be due to different dosing levels.

This study found that the circular RNA circCOL1A1 influences the formation of superior-quality brush hair in white goats by regulating hair follicle stem cell behavior and interacting with the miR-149-5p/CMTM3/AR axis.

In this study using a rat full-thickness burn model, the amnion bilayer dressing showed better healing and skin recovery than the standard protocol, including quicker complete healing and restored skin appendages.

This study found that exposing adult esophageal epithelial cells to skin stroma can induce them to transition toward a hair follicle identity, with HIF1a playing a crucial role in this conversion process.

This study reported that molecules from Zebrafish embryo cell differentiation can counteract neurodegeneration, regenerate tissues, and potentially reverse hair follicle damage in androgenetic alopecia.

In this study, researchers identified loss of function variants in the HR gene as likely causes of the distinct roaning hair coat seen in lykoi cats.

This study suggests that the InlB321/15 protein may accelerate wound healing by increasing cell proliferation and reducing wound closure time in both cell culture and mouse models.

This study suggests that paeoniflorin's protective effects on brain astrocytes may be mediated by TSPO and neurosteroids biosynthesis.

This study found that epigallocatechin-3-gallate (EGCG) may reduce paclitaxel-induced apoptosis in human dermal papilla cells by regulating microRNA expression related to apoptosis and cell proliferation.

This article reviews the identification and assessment of cutaneous drug reactions, emphasizing the importance of early recognition and the need for accurate diagnosis to prevent serious complications; it reports no new clinical results.

This study demonstrated that keratin extract can stimulate hair growth by inducing the anagen phase in telogenic mice.

This review of murine studies reports that γ-rays affect hair follicle pigmentation in mice throughout the hair cycle, while effects on hair structure may be obscured by aging.

In this study, only European-ancestry females showed a linear increase in cutaneous malignant melanoma risk with age, potentially due to the loss of HPV-infected androgenic follicles after menopause.

This animal study found that Laminaria japonica mixed with insulin-like growth factor-1 significantly promoted hair growth in mice, suggesting its potential use for treating alopecia pending further clinical trials.

This study found that topical application of partial proteasomal inhibitors accelerates hair growth by stabilizing β-catenin and disrupting the hair cycle's normal balance of activation and quiescence.

This article discusses the complex biological functions and social significance of hair follicles and reports no new research findings, emphasizing their role in health, disease, and a substantial beauty industry.

This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.

This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.

In this study, 5α-reductase inhibitors were found to have no significant impact on preventing tumorigenesis or progression in in vitro models of urothelial cancer.

Sex hormones might influence bladder cancer development, and aromatase inhibitors could increase risk in postmenopausal women.

This article reviews the possible therapeutic activities of Angelica gigas Nakai root extracts and their components, noting their potential effects on neuro-cognitive, metabolic, and other health conditions, and reports no new clinical results.

In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.

This review discusses the mechanisms of hair repigmentation and reports no clinical results; the authors suggest further research into topical treatments for reversing gray hair.

This review discusses the role of the mTORC1 pathway in acne pathogenesis in relation to diet and reports no new results.

This study reports that short exposure to vibration causes epithelial cells to retract filopodia, concentrate actin at their edges, and increase expression of the protease calpain, suggesting a mechanism for vibration-induced pain relief.

This study found that skin surface lipids contain measurable mRNAs, providing a non-invasive way to study skin diseases, with specific gene expression changes observed in atopic dermatitis patients.

In this study, researchers used an evolutionary-rate-based method to identify genetic elements associated with reduced hair in mammals, finding a dichotomy between accelerated coding sequences and noncoding regulatory elements influencing hair growth.

This review discusses the role of dermal macrophages in stress-induced hair regeneration and reports no new clinical findings, highlighting the need for further research into macrophage dynamics for potential hair loss therapies.

This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.

This study found that ethanolic asiasari radix extract may induce apoptosis in G361 melanoma cells through ROS-dependent regulation of p53, suggesting potential as a medicinal option for melanoma.