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Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Fat cells are important for tissue repair and stem cell support in various body parts.

FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Mice with human gene experienced hair loss when treated with DHT.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Blocking a specific protein signal can make hair grow on mouse nipples.

Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Plant-based ingredients are effective and safe for modern skincare products.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.

Raspberry ketone may help grow hair and improve skin elasticity.

GLI2 increases follistatin production in human skin cells.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Adrenal disorders can cause lasting brain and behavior issues in children.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.