research Clinical Translation of Microbiome Research in Alopecia Areata: A New Perspective
Further research is needed to understand how the microbiome affects hair loss in Alopecia Areata.
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research Metabolomic Biomarkers in Women with Polycystic Ovary Syndrome: A Pilot Study
Certain metabolites are lower in women with PCOS and could be potential markers for the condition.
research Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration
Regenerative cosmetics can improve skin and hair by reducing wrinkles, healing wounds, and promoting hair growth.
research Quantitative Single-Cell Approaches to Stem Cell Research
New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
research Platelet-Rich Plasma for Alopecia and Hair Restoration
Platelet-Rich Plasma (PRP) therapy can effectively treat various hair loss conditions, improve hair count, thickness, and density, and potentially speed up results when combined with surgical techniques.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research In-Silico Cardiac Aging Regulatory Model Including MicroRNA Post-Transcriptional Regulation
Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
research Evolving Approaches to Profiling the Microbiome in Skin Disease
New technologies help us better understand how skin microbes affect skin diseases.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research HPTLC Method Validation for Simultaneous Determination of Tamsulosin Hydrochloride and Finasteride in Bulk and Pharmaceutical Dosage Form
Created accurate method to measure tamsulosin hydrochloride and finasteride in tablets.
research A Computationally Inferred Regulatory Heart Aging Model Including Post-Transcriptional Regulations
Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
research Human Gene Correlation Analysis: A Tool for the Identification of Transcriptionally Co-Expressed Genes
The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
research The Rotterdam Study: 2018 Update on Objectives, Design, and Main Results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Drug Repositioning: New Opportunities for Older Drugs
Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
research Tracing Immune Cells Around Biomaterials With Spatial Anchors During Large-Scale Wound Regeneration
Immune cells are essential for skin regeneration using biomaterial scaffolds.
research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation
Human skin xenografting could improve our understanding of skin development, renewal, and healing.
research Fibroblasts: Origins, Definitions, and Functions in Health and Disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Stem Cell-Derived Exosomes: Emerging Therapeutic Opportunities for Wound Healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
research Scabicidal Potential of Coconut Seed Extract in Rabbits via Downregulating Inflammatory/Immune Cross-Talk: A Comprehensive Phytochemical/GC-MS and In Silico Proof
Coconut seed extract may effectively treat scabies in rabbits by killing mites and reducing inflammation.
research Exploring the Gut Microbiome and Metabolome in Individuals with Alopecia Areata
Alopecia Areata is linked to specific gut bacteria and metabolites, indicating a complex gut microbiome.
research Alterations in Transcriptome and Antioxidant Activity of Naturally Aged Mice Exposed to Selenium-Rich Rice
Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.
research The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research Hair Cell Toxicology: With the Help of a Little Fish
Zebrafish larvae are used to study and find treatments for ear cell damage because they are easier to observe and test than mammals.
research Mapping of Cis-Acting Expression Quantitative Trait Loci in Human Scalp Hair Follicles
Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.
research Commensal Microbiome Promotes Hair Follicle Regeneration by Inducing Keratinocyte HIF-1α Signaling and Glutamine Metabolism
Skin bacteria help hair regrow by boosting cell metabolism.
research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Identification of a Recurrent Nonsense Mutation in HR Gene Responsible for Atrichia with Papular Lesions in Two Kashmiri Families
A mutation in the HR gene causes a rare form of irreversible hair loss in two Kashmiri families. Whole exome sequencing is effective for finding such mutations.
research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine
The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.