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This report presents a case where a patient with Omenn syndrome, complicated by cytomegalovirus infection, was successfully treated using reduced intensity conditioning allogeneic HSCT from a sibling donor.

This review discusses Omenn syndrome, a form of severe combined immunodeficiency, highlighting its immunopathology and genetic defects without presenting new clinical results.

This case report describes a 10-month-old boy with VACTERL association and athymia who developed Omenn syndrome, highlighting the complex overlap of these conditions and the challenging clinical course due to profound T-cell immunodeficiency.

This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.

In this study, Ser516 phosphorylation of Artemis was found predominantly in the outer root sheath keratinocytes of hair follicles, suggesting a role in regulating human epidermal appendages.

Artemis dysfunction might cause hair loss through telomere shortening.

This study reported that alopecia occurred in 2.5% of patients with mycosis fungoides or Sézary syndrome, with some cases resembling alopecia areata and others associated with specific skin lesions.

In this study, hyperandrogenemia in young women with polycystic ovary syndrome was linked to higher blood pressure, independent of factors like age, insulin resistance, obesity, or dyslipidemia.

This review outlines the underlying pathophysiology and treatment options for the androgen excess and reproductive and metabolic manifestations of polycystic ovary syndrome, but reports no clinical results.

In this study, distinct metabolic profiles were identified in women with PCOS, suggesting potential biomarkers for diagnosis based on changes in lipid and androgen metabolism.

This study suggests that sexual dimorphism in adipose tissue functions may be linked to androgen levels, as women with PCOS demonstrated a more masculine adipokine expression pattern.

This study found that women with polycystic ovary syndrome in China had elevated androgen levels compared to healthy controls, and suggests body weight management and SHBG and FAI testing are recommended for these women.

This study observed that women with PCOS from Khyber Pakhtunkhwa had significantly higher serum PSA levels, which positively correlated with hirsutism, testosterone, and DHEAS levels compared to healthy controls.

This case report describes a 4-year-old boy with Netherton syndrome, where trichoscopy importantly aided diagnosis and is recommended for all children with erythroderma.

Early skin biopsy helps diagnose and manage severe skin conditions in babies.

This review discusses androgenetic alopecia and alopecia areata through a systems biology lens, emphasizing the role of multi-omics data integration to explore molecular mechanisms and potential therapeutic strategies, but offers no new clinical results.

In this study, skin manifestations were observed in 48% of children with primary immunodeficiency disorders, often providing crucial diagnostic clues for early identification of these conditions.

This review discusses the relationship between ectodermal alterations and immunodeficiencies, particularly the roles of hyper-IgE syndrome, ectodermal dysplasia, and FOXN1 gene mutations, but it presents no new research findings.

This meta-analysis reported that finasteride 1 mg/day significantly increased hair count in male androgenetic alopecia compared to placebo, but highlighted persistent sexual side effects and associated depression risk.

In this study, serum omentin-1 levels were significantly higher in females with idiopathic hirsutism compared to those with PCOS and healthy controls.

This study found that trichoscopy can diagnose genetic hair shaft abnormalities without plucking or cutting hair, by visualizing characteristic features in a single session.

This guideline provides a concise evidence-based overview of various aspects of polycystic ovary syndrome, including diagnosis and follow-up of secondary effects, but reports no new clinical results.

This guide provides a comprehensive approach to diagnosing periocular hair disorders, which can range from benign conditions to those posing serious health risks.

This review discusses the potential of targeting glucocorticoid action as a treatment strategy for obesity and type-2 diabetes, highlighting promising animal study results but reports no new clinical findings.

The document describes various skin conditions, their features, and treatments but lacks detailed study size information.

This article provides issue information for the September 2020 edition of the British Journal of Dermatology and contains no new research findings.

This index of Harper's Textbook of Pediatric Dermatology, Fourth Edition, provides no clinical results or new findings.

This handbook of dermatology provides a comprehensive practical manual for dermatologists, but reports no new research findings.

This article reviews the genetic basis, diagnostic approaches, and treatment options for nude severe combined immunodeficiency, but does not present any new research findings.

This study suggests that Artemis, particularly phosphorylated at serine 516, may have roles in hair follicle growth by influencing differentiation, proliferation, apoptosis, and cell cycling.