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210-240 / 1000+ resultsresearch Within-person changes of cortisol, dehydroepiandrosterone, testosterone, estradiol, and progesterone in hair across pregnancy, with comparison to a non-pregnant reference group
This study found that progesterone levels were higher and increased significantly throughout pregnancy, contrasting with stable levels in non-pregnant women.
research Characterization of polycystic ovary syndrome among Flo app users around the world
This study found that bloating is the most frequently reported symptom and a main predictor of polycystic ovary syndrome among women using the Flo app across five countries.
research Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons
This study found that neurotrophin-4 regulates Cav3.2 T-current expression in D-hair neurons via TrkB receptor activation, highlighting its role in mechanosensitive function.
research Use of Robotic Surgery in Plastic and Reconstructive Surgery: A Narrative Review
This study highlights the potential benefits and current limitations of robotic systems in nipple-sparing mastectomies, noting their promise in reducing surgeon fatigue but pointing out challenges such as longer operating times, high costs, and limited haptic feedback.
research Alopecia Areata After Initiation of Secukinumab Therapy for Plaque Psoriasis
In this case report, a 64-year-old woman developed alopecia areata after starting the IL-17A inhibitor secukinumab for psoriasis, highlighting a potential rare side effect of this treatment, with only three similar cases reported in the literature.
research A machine learning and network framework to discover new indications for small molecules
This study presents a computational approach, CATNIP, which repurposes drugs using only their biological and chemical information, predicting new uses like adrenergic uptake inhibitors for Parkinson's and vandetanib for Type 2 Diabetes.
research Deciphering the microbiology of hidradenitis suppurativa: a step forward towards understanding an enigmatic inflammatory skin disease
This review identifies that anaerobic bacteria from the gut and oral microbiota, not typical skin pathogens, are frequently present in hidradenitis suppurativa lesions, suggesting a role in inflammation and potential treatment targets.
research Exploring the efficacy of baricitinib in treating alopecia areata after failed Janus kinase inhibitor therapy
This study highlights the recent FDA approval of baricitinib as the first on-label treatment for severe alopecia areata, whereas previous treatments were off-label therapies like systemic steroids and immunosuppressants.
research Clinical Effects of Glucagon-Like Peptide-1 Agonist Use for Weight Loss in Women With Polycystic Ovary Syndrome: A Scoping Review
In this study, GLP-1 receptor agonists reduced BMI and improved metabolic and reproductive outcomes in women with PCOS, though the long-term effects remain unclear.
research An Unusual Case of Contact Dermatitis
In this case report, the authors linked acute psoriasiform contact dermatitis of the forehead and scalp to a low-laser light cap, identifying DMDE in the fabric as a likely cause.
research Granulocyte colony stimulating factor promotes scarless tissue regeneration
This study found that mice lacking the CXCR2 receptor regenerated tissue scarlessly in various injury models and that administering plasma or G-CSF from these mice to wild-type mice also reduced scarring, suggesting potential therapeutic strategies to improve human skin wound healing.
research Improved Humoral Immunity and Protection against Influenza Virus Infection with a 3d Porous Biomaterial Vaccine
Researchers demonstrated that a new vaccine platform using antigen-loaded hydrogels enhanced humoral immune responses in mice, producing stronger antigen-specific antibody levels compared to the conventional adjuvant Alum, and offering promising protective capabilities against influenza virus.
research Keratin 75 Is a Component of the LINC Complex and Has an Essential Role in Mediating the SOX2 Rapid Healing Response during Wound Repair
This study found that enhanced wound healing in oral mucosa involves a SOX2-regulated transcriptional network which includes increased expression of keratin K75, and interaction of K75 with the LINC complex may play a crucial role in promoting rapid wound repair.
research Hair transparency decoding in Asia: From stylists’ perception to in vitro measurement
This study clarified and quantified the concept of hair transparency using a validated mathematical model based on measurable hair properties and consumer perception data from stylists in Japan and China.
research Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor
This study found that mitochondrial oxidative phosphorylation in epithelial cells is necessary for proper enamel formation and odontoblast differentiation in developing incisor teeth in K320E-Twinkle Epi mice.
research Evaluation of bioequivalence of five 0.1 mg dutasteride capsules compared to one 0.5 mg dutasteride capsule: a randomized study in healthy male volunteers
This study found that five 0.1 mg dutasteride capsules are bioequivalent to one 0.5 mg dutasteride capsule in healthy adult males under fasting conditions, and both were well tolerated.
research Diverse northern Asian and Jomon-related genetic structure discovered among socially complex Three Kingdoms period Gaya region Koreans
This study reported the first paleogenomic data from Korea, revealing genetic diversity in ancient Koreans from the Gimhae region, with evidence of admixture between northern-Chinese Iron Age populations and Japanese-Jomon-related ancestry.
research Cosmetic surgery in men
This article discusses cosmetic surgeries offered to men in the UK and highlights potential risks but reports no new findings.
research Bi-compartmentalized stem cell organization of the corneal limbal niche
This study demonstrates that in vivo live imaging reveals how distinct stem cell activities in the limbal niche coordinate corneal regeneration.
research Matrix matching in quantitative bioanalysis by LC–MS/MS a dream or a reality?
This article reviews analysis techniques in LC-MS/MS and discusses the potential use of a novel in-sample calibration curve method, but reports no new experimental results.
research Ovarian vein sampling, and serum and urine testosterone monitoring in ovarian Leydig cell tumors: A report of two cases
In this study, two women with hyperandrogenic symptoms were found to have ovarian Leydig cell tumors after selective ovarian venous sampling and salpingo-oophorectomy, leading to a decline in testosterone levels post-surgery.
research Efficacy of subcutaneous injection of platelet-rich plasma in alopecia: A clinical and histological pilot study on a rat model with a six-month long-term follow-up experience
In this study, subcutaneous platelet-rich plasma injections improved hair density and histological markers of hair growth in hairless rats without causing local toxicity.
research A Comprehensive Review of GWASs of Human Hair Traits
Genetic studies on hair traits can improve understanding of health and disease.
research Optimizing hair care products and practices for Black patients with breast cancer: One size does not fit all
This review from JAAD highlights disparities in the effectiveness of hair preservation techniques for Black women undergoing chemotherapy, noting that current methods like scalp cooling often underperform due to structural differences in Black hair, and recommends tailored strategies such as adjusting hair preparation before treatment.
research Evolution and genetic architecture of sex-limited polymorphism in cuckoos
In this study, researchers found that the female plumage color variations in the common cuckoo are linked to the female-restricted genome and suggest this pattern is maintained by balancing selection, sharing ancestry with the oriental cuckoo.
research Support Group Participation Among Patients With Alopecia Areata
Support groups help people with alopecia areata feel better emotionally, but more awareness and access are needed.
research Why menopause is relevant to the rheumatologist
This article discusses the interaction between menopause and rheumatic diseases, emphasizing the need for rheumatologists to recognize menopausal symptoms and consider hormone replacement therapy in patient care, but it provides no new experimental results.
research Perifollicular inflammation and follicular spongiosis in androgenetic alopecia
This study observed that inflammation in androgenetic alopecia samples was similar to alopecia areata controls, but infundibular and isthmic inflammation were significantly more common in androgenetic alopecia cases.
research Injection of PRP (Platelet-rich plasma) as a treatment for androgenetic alopecia : a systematic review of the literature
This review analyzes existing clinical results on the use of platelet-rich plasma injections for treating androgenetic alopecia but reports no new findings; the authors emphasize the need for further controlled studies.