72 citations
,
December 1996 in “Journal of Investigative Dermatology” This study observed that human hair follicles were able to regenerate fiber-forming structures after the bulb was amputated and transplanted onto athymic mice, suggesting a general regenerative capacity.
21 citations
,
March 2017 in “Skin research and technology” In this study, extracting internal lipids from Caucasian hair fibers led to decreased water permeability, influenced by the fluidity of lipids.
8 citations
,
February 2005 in “Veterinary dermatology” This study suggests that hair loss in Chesapeake Bay retrievers is a breed-specific syndrome characterized by unique histological features and abnormal steroid production, possibly influenced by familial factors.
7 citations
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March 2019 in “Journal of cosmetic dermatology” This study found that African and Caucasian hair contain the most lipids, and depletion of these lipids leads to less water retention and increased water desorption, with Caucasian hair showing improved breaking tenacity after lipid extraction.
66 citations
,
August 2001 in “Experimental Dermatology” This study demonstrated that intact adult human dermal papillae can induce hair growth when implanted into mouse hair follicles, highlighting their potential for advancing hair follicle biology and therapeutic approaches.
29 citations
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October 2019 in “Journal of dermatological science” This review explores how cell and mouse models have contributed to understanding the mechanisms of human aging, particularly focusing on Hutchinson-Gilford Progeria Syndrome, and reports no new clinical results.
15 citations
,
January 2020 in “ILAR Journal” This review discusses the occurrence and impact of background histopathologic changes in nonhuman primate research, emphasizing the importance of understanding these factors to enhance study validity and interpretation.
January 2024 in “Pharmacoepidemiology” This study found that patients with rheumatoid arthritis taking tofacitinib had higher rates of serious adverse events compared to those with alopecia areata, highlighting the need for careful assessment when using it off-label for alopecia areata.
36 citations
,
March 2014 in “Annals of the Rheumatic Diseases” This study found that activating liver X receptors with an agonist reduced skin fibrosis in experimental models, particularly in inflammation-driven conditions, by inhibiting macrophage infiltration and interleukin-6 release.
2 citations
,
August 2025 in “Harm Reduction Journal” This study highlights the severe health risks and dependence associated with non-medical androgen use among gym-goers, stressing the need for specialized primary care and harm-reduction strategies due to potentially fatal outcomes even after prolonged cessation.
1 citations
,
March 2023 in “European Journal of Human Genetics” This retrospective study observed that patients with vascular EDS on long-term angiotensin II receptor blockers or beta-blockers experienced fewer vascular events compared to those without cardiac medication under similar lifestyle and emergency care advice.
June 2023 in “Journal of Face Aesthetics” This review discusses the potential role of platelet-rich fibrin in aesthetic and dental procedures but highlights the need for more rigorous future studies to confirm its effectiveness and safety.
July 2022 in “Institutional Repositories DataBase (IRDB)” 3D spheroid cells effectively test hair growth compounds like Minoxidil.
January 2019 in “Indian Journal of Dermatology, Venereology and Leprology” 32 citations
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January 2024 in “The Journal of Experimental Medicine” This study found that CXCL12+ fibroblast subsets in mouse skin play a critical role in recruiting neutrophils and defending against S. aureus infection, with similar fibroblast activity observed in human psoriatic skin.
85 citations
,
June 2017 in “Journal of Investigative Dermatology” This study found that Blimp1 plays a key role in promoting hair follicle morphogenesis and growth by mediating inductive signaling pathways in dermal papilla cells.
59 citations
,
September 2021 in “Journal of Allergy and Clinical Immunology” This study found IL-17/IL-36 signaling to be predominant in both endotypes of Netherton syndrome, with distinct molecular profiles between NS-ILC and NS-SE lesions, offering potential therapeutic targets.
10 citations
,
June 2013 in “Talanta” This study demonstrated a validated UPLC method for analyzing finasteride in low-dose drug products, highlighting methanol content and flow rate as critical factors for method robustness and accuracy.
April 2025 in “Journal of Pharmaceutical Investigation” In this study, injectable microdepots containing rapamycin and poly(lactic-co-glycolic acid) were developed and demonstrated to effectively promote hair regrowth in mice by sustaining drug release and inducing anagen phase transition in hair follicles through modulating autophagy and the Wnt/β-catenin pathway.
January 2024 in “Endocrine and metabolic science” This review explores the applicability of the current PCOS diagnostic criteria, highlighting the need to reassess these criteria in light of new evidence on the disorder's heterogeneity and potential subtypes.
July 2023 in “Journal of the Mexican chemical society” This study found that Hibiscus rosa-sinensis dried leaves extract displayed the strongest pancreatic lipase inhibitory activity among 37 tested plant extracts, showing potential as an anti-obesity agent with effects comparable to the pharmaceutical drug orlistat in reducing plasma triacylglycerol levels in rats.
May 2023 in “Clinical and translational neuroscience” This article summarizes current knowledge on treating neurological symptoms of post-COVID-19 syndrome, highlighting the lack of pharmaceutical options and reliance on non-drug therapies to manage symptoms like fatigue, cognitive impairment, and sleep disturbances.
30 citations
,
February 2022 in “Pharmaceutics” This review explores recent advancements in skin tissue engineering using 3D bioprinting, discussing current methods, bioink formulations, and outlining both achievements and limitations without presenting new clinical results.
3 citations
,
September 2025 in “Frontiers in Cardiovascular Medicine” This study reports that women with polycystic ovary syndrome, especially those with a hyperandrogenic pattern, are at a higher risk for cardiovascular disease compared to other PCOS patients, likely due to related metabolic comorbidities.
13 citations
,
September 2022 in “Journal of Animal Behaviour and Biometeorology” This article reviews the thermoregulation mechanisms in African and Asian elephants and highlights challenges from climate change, with no new empirical results presented.
6 citations
,
April 2023 in “Current Issues in Molecular Biology” This study identified three variants in the HR gene among Mexican patients with alopecia areata, with one novel variant potentially serving as a risk factor for the disease.
5 citations
,
May 2022 in “Biomedicines” This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.
2 citations
,
June 2022 in “Cells” The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.
May 2024 in “Journal of functional foods” In this laboratory study, coffee bean residue extract was observed to promote the proliferation of human hair follicle dermal papilla cells by activating autophagy, showing potential for treating hair growth disorders and hair loss.
13 citations
,
February 2022 in “JAMA Dermatology” This meta-analysis found that spironolactone use was linked to a decreased risk of prostate cancer but not to a significant risk increase for several other cancers, although the evidence certainty was low.