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Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.

Apple procyanidin applied to the scalp may help grow hair without side effects.

Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.

Procyanidin oligomers can protect hair from oxidative damage and could be good for hair care products.

A small molecule can strengthen fine hair, making it more resistant and natural-feeling.

Taxifolin-based treatments help skin heal after chemical burns.

Some off-label treatments increase hair density, but long-term safety unknown.

Created large amounts of grape seed compounds using a new method.

Using laccase to add poly(tyrosine) to wool makes it less likely to shrink and stronger.

Certain substances that block a specific protein help promote hair growth.

Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.

Extracts from Cercidiphyllum japonicum wood can stimulate mouse hair cell growth like common hair growth treatments.

Apple-derived procyanidin B-2 can safely promote hair growth in men.

Procyanidin B-2 is safe to use on skin as a hair growth product.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.

Some plant-based ingredients may help with hair growth and care, but more research is needed to confirm their effectiveness.

Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.